Scientist - LC-MS Specialist/Analytical Chemistry

Amgen; København; On-site; DKK 654,000 - 884,000; Full time

Job summary

Amgen Copenhagen Research (ARC) seeks a candidate to join the Analytics team, operating LC-MS systems and automated sample preparation equipment to enable high-throughput data delivery and method development.

You will work cross-functionally with DEL-technology, parallel synthesis, medicinal chemistry and biology, maintain instruments, supervise users, and deliver high-quality results with meticulous data organization. The role is based in Copenhagen, spanning two Østerbro offices.

Qualifications

• M.Sc. or B.Sc. in a relevant technical or scientific discipline with at least three years' experience maintaining and operating LC instruments.
• Laboratory technicians with at least ten years of relevant experience and well-documented training may also be considered.

Responsibilities

• Daily care of ARC analytical and prep LC-MS.
• Keeping LC and MS instruments in excellent operational state.
• Software support for all LC and MS based software packages.
• Supervision of LC-MS users.
• Purification of oligo conjugates and other compounds on LC systems.
• Keeping track of spare parts for all instruments.

Skills

LC-MS operation

Analytical instrumentation

English communication

Team collaboration

Data organization

Troubleshooting

Education

M.Sc./B.Sc. in a relevant technical or scientific discipline

Tools

Agilent ChemStation

MassHunter

Waters MassLynx

Shimadzu LabSolutions

ACD/Labs

Mnova

Job description

Career Category

Research

Job Description

Amgen is one of the world’s leading independent biotechnology companies. For four decades, Amgen has pioneered biotechnology breakthroughs to bringstate-of-the-artmedicines from laboratory to the patient. Amgen Research Copenhagen (ARC),through our DNA Encoded Library (DEL) technology, iscontributing significantly to Amgen’s many smallmolecule drug discovery projects from hit discovery all the way to drug candidate selection.

We are currently seeking acandidateto join a team thatoperates, supports, troubleshoots, andmaintainsanalytical instruments, while providing expert instrument guidance to users runningsamples. In addition, the candidate will support the effective use of various LC–MS software packages.

If you are passionate, analytical, resourceful,practical,goal-oriented, open-minded, conscientious, willing to go the extra mile, enjoy working in the lab in a dynamic environment, and have a desire to contribute to groundbreaking scientific research within a new field of drug discovery, we may have a position for you.

As a member of the Analytics team,you will help us setup and operate LC-MSsystems and various automated sample preparation equipment to ensurehigh-throughput acquisition, analysis and purification of small molecule including oligo conjugates to deliverhigh-qualitydata, take part in method development and implementation of new analytic instruments. The position will primarily involve maintenance and setup of LC-MS systems, but also method development and testing of new setups. You will be working cross-functionally with internal groups specializing in DEL-technology, parallel synthesis, medicinal chemistry and biology, and you willparticipatewith your analyticalexpertisein the process of identifyingand purifying various compounds.

Specifically, tasks will include:

• Daily care of ARC analytical and prep LC-MS.
• Keeping LC and MS instruments, including CLNDdetectors, in excellent operational state.
• Software support for all LC and MS based software package
• Supervision of LC-MS users
• Purification of oligo conjugates and other compounds on LC systems
• Keeping track of spare parts for all instruments

We offer a highly rewarding and stimulating environment in a world-class drug discovery organization.The position is based across our two Østerbro offices, 1.3 km apart,about 4minutes bybike.

The employee will report toScientificAssociateDirector, MichaelGodskesen. For further information contact HRSr Manager,Rachel Allen ([e-mail])

Qualifications:

Preferably, the candidate should hold an M.Sc. or B.Sc. degree in a relevant technical or scientific discipline and have at least three years of experiencemaintainingand operating LC instruments from multiple suppliers. Laboratory technicians with at least ten years of relevant experience and well-documented training may also be considered.

The ideal candidate will have:

• Proficiency in running analytical aswell as preparative samples on various LC-MSplatforms
• In depth understanding of liquid chromatography and Mass Spectrometry
• On hands experience working and maintenance of different LC-MS systems
• Competence related to manual and automated sample preparation
• Proficiency in AgilentChemStationandMassHuntersoftware
• Familiaritywith Waters MassLynx software
• Knowledge of Shimadzu LabSolutions software
• Experience working with third party analytical software ACD Labs,Mnovaor similar
• A talent for tidiness, data organization etc.
• Excellent collaboration and team player skills
• Thrives in a fast-changing environment where priorities and location can change throughout the day
• Excellent English communication skills
• A confident communicator committed to delivering high-quality results

Salary Range

653,517.40DKK-884,170.60DKK