Postdoc in Epigenetic Regulation | Single-Cell Multi-Omics

Aarhus Universitet; Aarhus; On-site; DKK 480,000 - 600,000; Full time

Benefits offered by this job

Well-developed research infrastructure

Interdisciplinary collaboration

Job summary

Aarhus University’s Department of Molecular Biology and Genetics invites applications for a 3-year postdoctoral position in chromatin biology and epigenetic gene regulation. The project focuses on developing single-cell multi-omics approaches to uncover regulators upstream of epigenetic writers and erasers during embryonic development.

The role involves Cas9-based perturbation, method development, and downstream verification in transgenic cell lines, with a team including two PhD students.

Qualifications

• PhD required in molecular biology, genetics, epigenetics, developmental biology, or closely related field.
• Experience planning and executing experiments in chromatin/epigenetics, stem cell culture, single-cell sequencing, method development, flow cytometry, and/or CRISPR perturbations.
• Strong background in embryonic development and ability to drive a research project.

Responsibilities

• Design and execute experiments involving Cas9 perturbation and single-cell multi-omics method development.
• Develop and optimize functional screening pipelines to identify regulators of epigenetic state establishment.
• Collaborate across wet lab, proteomics, and dry lab to integrate screening discoveries.
• Train junior group members and contribute to lab supervision.

Skills

ChIP-seq

CUT&RUN/Tag

Single-cell sequencing

CRISPR perturbations

Stem cell culture

Data analysis

Team supervision

Education

PhD in molecular biology or related field

Job description

Aarhus University’s Department of Molecular Biology and Genetics invites applications for a 3-year postdoctoral position in chromatin biology and epigenetic gene regulation. The project focuses on developing single-cell multi-omics approaches to uncover regulators upstream of epigenetic writers and erasers during embryonic development.

The role involves Cas9-based perturbation, method development, and downstream verification in transgenic cell lines, with a team including two PhD students.