Postdoc: Multi-Omics Bioinformatician in Liver Cancer

Region Hovedstaden; Hillerød; On-site; DKK 520,000 - 620,000; Full time

Benefits offered by this job

Fully funded position

International mobility

Conference attendance

State-of-the-art infrastructure

Job summary

Region Hovedstaden invites applications for a Postdoctoral Bioinformatician / Computational Biologist based at Rigshospitalet, Copenhagen, Denmark. The position is funded for three years and focuses on bridging functional genomics with population genetics under an Novo Nordisk Foundation project.

You will lead bioinformatic analyses of CRISPR screens and large biobank data, collaborate with wet-lab and clinical teams, and work across BRIC and Rigshospitalet infrastructure to study liver cancer

Qualifications

• A PhD (or MD PhD) in Bioinformatics, Computational Biology, Human Genetics, Biostatistics, Data Science, or a related quantitative field.
• Experience with primary analysis of high-throughput sequencing data (e.g., CRISPR screening data, bulk/single-cell/spatial transcriptomics).
• Insight into and experience with large-scale human genetic epidemiology, including GWAS, rare-variant burden testing, and PheWAS is required.
• High proficiency in R and/or Python, shell scripting, reproducible workflow managers, and working in High-Performance Computing (HPC) environments.
• Excellent written and oral communication skills in English.

Responsibilities

• Lead the bioinformatic pipeline for processing and statistical evaluation of high-throughput multi-modal CRISPR screens (KO, CRISPRi, CRISPRa).
• Conduct large-scale human genetic analyses (rare variant burden tests, GWAS, PheWAS) on biobank datasets (>2 million individuals).
• Analyze spatial transcriptomics, single-cell, and multi-omics data from human MASLD-HCC tissue cohorts.
• Collaborate closely with wet-lab postdocs, PhD students, and international partners.

Skills

PhD in Bioinformatics

R

Python

HPC

English communication

Education

PhD in Bioinformatics

Tools

R

Python

Shell scripting

Workflow managers

HPC

Job description

Region Hovedstaden invites applications for a Postdoctoral Bioinformatician / Computational Biologist based at Rigshospitalet, Copenhagen, Denmark. The position is funded for three years and focuses on bridging functional genomics with population genetics under an Novo Nordisk Foundation project.

You will lead bioinformatic analyses of CRISPR screens and large biobank data, collaborate with wet-lab and clinical teams, and work across BRIC and Rigshospitalet infrastructure to study liver cancer