PhD: 3D Cochlear Histopathology in Aging & Disease

Technical University of Denmark

Kongens Lyngby

On-site

DKK 320,000 - 360,000

Full time

9 days ago

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Job summary

Technical University of Denmark (DTU) Health Tech seeks a motivated researcher for a 3-year PhD project on cochlear pathology in ageing and systemic disease. You will work in the Centre for Auditory Neuroscience within the Hearing Systems section, applying advanced preclinical immunolabelling and light-sheet microscopy in rodent models and collaborating with diverse experts.

You will design experiments, develop imaging workflows, analyze data, and contribute to publications, conferences, and

Qualifications

Two-year master’s degree (120 ECTS) or equivalent in neuroscience, medicine or related field.
Hands-on experience with laboratory rodents in a research setting.
Experience with immunofluorescent tissue labelling and tissue processing.
Experience acquiring and evaluating fluorescence microscopy data.
Aptitude for quantitative analysis through scripting, image analysis or statistics.
Strong interest in inner-ear pathology and independent research initiative.
Excellent written and spoken English; ability to collaborate in an interdisciplinary team.
Cover letter, CV, transcripts and degree diplomas.

Responsibilities

Design and perform studies in rodent models of hearing loss and systemic disease.
Develop and validate tissue clearing and whole-organ immunolabelling for the cochlea.
Acquire light-sheet microscopy datasets from intact cochleae.
Develop quantitative measures of cochlear pathology and image-analysis pipelines.
Interpret findings in relation to auditory function and disease markers.
Publish papers, present at conferences, and contribute to teaching and supervision.
Complete 30 ECTS of PhD coursework and a 3–6 month research stay at a partner lab.