Senior Scientist (f/m/x) in Metabolomics and Tracer Analytics

Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH); Oberschleißheim; Hybrid; EUR 85,000 - 110,000; Full time

Benefits offered by this job

Career development

International staff service

Scientific resources

Family support

Health initiatives

30 days annual leave

Job summary

Helmholtz Zentrum München, Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) seeks a Senior Scientist (f/m/x) in Metabolomics and Tracer Analytics to build tracer metabolomics and fluxomics, expanding capabilities in the Core Facility Metabolomics and Proteomics. The role includes method development, staff training, and collaboration across programs.

You will design isotope tracing experiments, develop data workflows, supervise analyses by LC-MS/MS and GC-MS/MS, and mentor scientific

Qualifications

• PhD in Biochemistry, Analytical Chemistry, Systems Biology, or a related field.
• Demonstrated expertise in tracer metabolomics and/or metabolic flux analysis using 13C, 15N and/or deuterium-labelled substrates.
• Hands-on experience across the tracer workflow, from experimental design to data analysis and interpretation.
• Experience with LC-MS/MS and GC-MS/MS instrumentation, including operation, optimization and troubleshooting.
• Hands-on experience with mammalian cell culture and relevant matrices for metabolomics analyses.
• Solid understanding of cellular metabolism and metabolic pathways, with ability to interpret data.
• Computational skills in R and/or Python.
• Experience with El-MAVEN, XCMS, MetaboAnalyst, INCA or 13CFLUX2.
• Experience in training users or supervising staff.
• Clear and engaging communication and customer-oriented service.

Responsibilities

• Design, establish and optimise state-of-the-art stable isotope tracing and flux experiments.
• Develop and apply data analysis workflows for tracer experiments, isotopologue data analysis, and metabolic flux modeling.
• Perform and supervise metabolomics, lipidomics and fluxomics analyses using LC-MS/MS and GC-MS/MS.
• Develop and maintain analytical methods, SOPs and QC procedures.
• Advise researchers on study design, tracer selection and experimental strategies.
• Support interpretation of results, publications and grant applications.
• Train and educate users in tracer metabolomics methodologies.
• Supervise and mentor scientific and technical staff.

Skills

Tracer metabolomics

Metabolic flux analysis

LC-MS/MS

GC-MS/MS

R

Python

El-MAVEN

XCMS

MetaboAnalyst

INCA

13CFLUX2

Training staff

Data analysis workflows

Education

PhD in Biochemistry, Analytical Chemistry, Systems Biology, or related field

Tools

LC-MS/MS

GC-MS/MS

El-MAVEN

XCMS

MetaboAnalyst

INCA

13CFLUX2

Job description

Senior Scientist (f/m/x) in Metabolomics and Tracer Analytics

103040

Full time

39 hrs/week

Neuherberg near Munich

Partially Remote Work possible

At Helmholtz Munich, we develop groundbreaking solutions for a healthier society in a rapidly changing world. We believe that diverse perspectives drive innovation. Through strong partnerships, we accelerate the transfer of new ideas from the lab to real-life applications, improving lives.

We are looking to strengthen and expand the portfolio of functional omics services in ourCore Facility Metabolomics and Proteomicsand are seeking a highly motivated and accomplishedSenior Scientist (f/m/x)to establish and expand tracer metabolomics and fluxomics capabilities, supporting researchers across Helmholtz Munich and beyond.

Our new colleague will be a team player enthusiastic about developing new analytical methods and advancing state-of-the-art metabolomics technologies. Training users, teaching advanced analytical methods, supervising scientific and technical staff and presenting results internally and externally are part of the job. The position reports directly to the Head of the Metabolomics and Proteomics Core Facility and will be available from January 2027.

Your tasks & responsibilities

• Design, establish and optimise a state-of-the-art stable isotope tracing and flux experiment services.
• Develop and apply data analysis workflows for stable isotope tracer experiments, isotopologue data analysis, and metabolic flux modeling.
• Perform and supervise metabolomics, lipidomics and fluxomics analyses using LC-MS/MS and GC-MS/MS platforms.
• Develop and maintain analytical methods, SOPs and quality-control procedures.
• Advise researchers on study design, tracer selection and experimental strategies.
• Support investigators in interpretation of results, publications and grant applications.
• Train and educate users in tracer metabolomics methodologies.
• Supervise and mentor scientific and technical staff supporting facility operations.

Your profile

• PhD in Biochemistry, Analytical Chemistry, Systems Biology, or a related field.
• Demonstrated expertise in tracer metabolomics and/or metabolic flux analysis using 13C, 15N and/or deuterium-labelled substrates.
• Hands-on experience across the tracer workflow, from experimental design to data analysis and interpretation.
• Experience with LC-MS/MS and GC-MS/MS instrumentation, including operation, optimization and troubleshooting.
• Hands-on experience with mammalian cell culture and the processing of other relevant biological matrices (e.g., tissues, biofluids) for metabolomics analyses.
• Solid understanding of cellular metabolism and metabolic pathways, with the ability to interpret data in a biological context.
• Computational skills for metabolomics and fluxomics data analysis, including proficiency in R and/or Python.
• Experience with software such as El-MAVEN, XCMS, MetaboAnalyst, INCA or 13CFLUX2 (or comparable tools).
• Experience in training users, teaching, or supervising scientific or technical staff.
• Clear and engaging communication to internal and external audiences.
• Strong commitment to customer-oriented scientific service and collaborative research.

If you fulfill all the requirements, you may be eligible for a salary grade of up to E 14. Social benefits are based on the Collective Wage Agreement for Public-Sector Employees (TVöD). The position has an (initial) fixed term of 2 years, with the possibility of moving to a permanent contract.

We offer

• The opportunity to build and shape a new strategic capability in tracer metabolomics and fluxomics.
• Access to state-of-the-art mass spectrometry infrastructure and large translational research programs.
• Close interaction with leading scientists in metabolic health, precision prevention, bioengineering and health AI.
• A highly collaborative and international research environment with extensive opportunities for scientific networking.

Managing Director Mike Frieser:

“We believe that diversity is the key to groundbreaking research and innovative solutions. Our flexible working models and remote options create a supportive environment for balancing work and family life. For us, contributing to a healthier society in such an inspiring workplace is truly meaningful.”

Get to know us

Benefits

• Career Development: Postdoc program, scientific training & career center with tailored offers
• International Staff Service: Support with the relocation and integration process in Germany
• Scientific Resources: State-of-the-art infrastructure and Core Facilities
• Family Support: On-site kindergarten, holiday care, care for the elderly
• Health Promotion: Sports, company doctor, mental health initiatives
• Recreation: 30 days annual leave, flexi days, plus public holidays

If you have any questions, feel free to contact Stefanie Hauck, [e-mail], who will be happy to help.