Research Associate Oligonucleotide Chemistry

AIRNA Bio Germany GmbH; Tübingen; Vor Ort; Vertraulich; Vollzeit

Zusammenfassung

A biotechnology company in Tübingen is seeking a motivated individual to support oligonucleotide synthesis and develop efficient processing workflows. This role requires an MSc in organic chemistry or related field, along with strong wet lab skills. Candidates must excel in communication and attention to detail. The position offers attractive compensation and the opportunity to contribute to impactful research.

Leistungen

Exciting role in high-impact research

Collaborative and diverse team

Attractive compensation and stock options

Qualifikationen

• Familiarity with oligonucleotide chemistry is a plus.
• Solid wet lab skills including pipetting and manipulating liquids.
• Hands-on approach and precision.

Aufgaben

• Support the synthesis of oligonucleotides for research.
• Develop processing workflows to enhance efficiency and quality.
• Run systematic reaction optimizations on automated synthesizers.
• Document and report experimental results.

Kenntnisse

Oligonucleotide chemistry

Wet lab skills

Team player

Communication skills in English

Attention to detail

Ausbildung

MSc in organic chemistry or related

BSc with 2 years of industry experience

Tools

HPLC equipment

Oligonucleotide synthesizers

Jobbeschreibung

AIRNA is a biotechnology company with a mission to be the leading RNA editing company delivering precision therapies to patients with rare and common diseases.

AIRNA is harnessing advances in genetics to develop transformative RNA-editing medicines that improve human health. Our proprietary platform is based on groundbreaking research by pioneers of the field and company co-founders Thorsten Stafforst (University of Tübingen) and Jin Billy Li (Stanford University) and enables optimal potency, safety, and delivery. AIRNA is advancing a robust pipeline of therapeutic candidates that are designed to provide functional cures for severe or chronic diseases by repairing harmful genetic variants or introducing beneficial variants promote optimal health.

AIRNA has raised $245 million in financing from a world-class syndicate of investors including Arch Venture Partners, Forbion, Venrock Healthcare Capital Partners, RTW Investments, Nextech Invest, and ND Capital. We value teamwork, resilience, excellence, human, and health, and have a diverse team at both our headquarters in Cambridge, MA and our research operations in Tübingen, Germany.AIRNA Bio Germany GmbH is seeking a highly motivated and collaborative

Tasks

• Support the synthesis of oligonucleotides on mouse and non-human primate (NHP) scale (Mermade, Cytiva, K&A) for research and pre-clinical use
• Apply and develop processing workflows and procedures to enhance time efficiency and product quality
• Run systematic reaction optimizations on automated DNA synthesizers
• Perform conjugation reactions of small molecules with oligonucleotides
• Document and report experimental results
• Write standard operating procedures (SOP’s)
• Maintain a clean and safe working environment
• Pro-actively communicate with other team members and colleagues within the company

Requirements

• MSc in organic chemistry or related (or BSc with min. 2 years of industry experience)
• Familiarity with oligonucleotide chemistry and previous work experience is considered a plus
• Solid wet lab skills: pipetting, manipulating liquids, handling chemicals, work in laminar flow hood etc.; familiarity with HPLC equipment is considered a plus, familiarity with oligonucleotide synthesizers is a big plus
• Hands-on approach and can-do attitude, precision, and attention to detail
• Team player with excellent communication skills in spoken and written English, German is a plus
• A valid work permit for Germany is mandatory

Benefits

• An exciting role in a promising, high-impact research field.
• The opportunity to contribute to the development of future medicines.
• Work within a fast-growing startup that values innovation and scientific excellence.
• Collaborate with a diverse, enthusiastic, and international team.
• Be part of the ONE AIRNA culture.
• Attractive compensation, stock options, and additional benefits.
• The position involves working across both Germany and the US and intercultural exchange opportunities.

The position is based in Tübingen, Germany.