Research Associate (m/f/d) - Laboratory and Project Coordinator Molecular Biology (E 13 TV-L, full-time)

Hochschule für angewandte Wissenschaft und Kunst Hildesheim/Holzminden/Göttingen

Hildesheim

On-site

EUR 52,000 - 70,000

Full time

5 days ago
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Job summary

HAWK University of Applied Sciences and Arts Hildesheim/Holzminden/Göttingen sucht eine/n Forschungsassistent/in (m/w/d) zur Koordination des Labor- und Forschungsprozesses im Molekularbereich des FEMTOMICS-Projekts. Sie arbeiten an der Planung, Durchführung und Auswertung molekularbiologischer Experimente.

Sie bringen Expertise in Genomik, Biochemie und Zellbiologie mit, arbeiten eigenständig und koordinieren externe Analysen sowie Interdisziplinäre Zusammenarbeit.

Qualifications

  • Masterabschluss in Biologie, Biochemie oder Molekularbiologie; Doktorgrad vorteilhaft.
  • Nachgewiesene unabhängige Forschungserfahrung nach dem Masterabschluss.
  • Erfahrung in DNA/RNA-Analysen, (q)PCR, ChIP oder ähnliche Protein-DNA-Interaktionsmethoden.

Responsibilities

  • Verantwortung für Planung, Durchführung und Auswertung von molekularbiologischen, Genomik- und Biochemie-Arbeiten im FEMTOMICS-Projekt.
  • Optimierung und Validierung von Methoden zur Untersuchung Protein-DNA-Interaktionen.
  • Koordination von Arbeitsabläufen, Zusammenarbeit mit Interdisziplinären Partnern und externen Dienstleistern.

Skills

Molekularbiologie
Genomik
Zellbiologie
Bioinformatik
DNA/RNA Analyse
NGS-Workflow

Education

Masterabschluss in Biologie/Biochemie/Molekularbiologie
PhD vorteilhaft

Tools

ChIP-Seq
NGS
Nanopore sequencing
LC-MS/MS

Job description

Research Associate (m/f/d) - Laboratory and Project Coordinator Molecular Biology (E 13 TV-L, full-time)

Göttingen

At HAWK University of Applied Sciences and Arts Hildesheim/Holzminden/Göttingen, Faculty of Engineering and Health, Göttingen campus, the following position in the ERC Advanced Grant project FEMTOMICS is to be filled at the earliest possible date, for a fixed term of three years:

Within the ERC Advanced Grant project FEMTOMICS, we are developing novel photonic and molecular analytical methods for the high-resolution investigation of dynamic protein-DNA interactions. Femtosecond laser-based crosslinking (fliX) is combined with complementary methods in quantitative and structural proteomics (LC-MS/MS), genomics and sequencing (ChIP-Seq, nanopore sequencing), and bioinformatics for multiomics data integration and analysis to characterise protein-DNA interactions at the structural and functional levels. The aim is to make previously inaccessible dynamic molecular processes experimentally measurable and thereby establish new foundations for investigating regulatory mechanisms in biological and disease-relevant systems.

For the scientific development and coordination of the molecular biology work package within FEMTOMICS, we are seeking an enthusiastic scientist with proven experimental expertise in molecular biology, genomics, biochemistry, and cell biology. The position combines the independent development and execution of scientific experiments with responsibility for experimental planning, laboratory workflow management, the coordination of external analyses, and interdisciplinary collaboration across physics, proteomics, and bioinformatics. The work will contribute to the further development of the FEMTOMICS platform and create new opportunities for the structural and functional characterisation of protein-DNA interactions and the investigation of disease-relevant regulatory processes.

Ihre Aufgaben
  • Scientific responsibility for the planning, execution, and evaluation of molecular biology, genomics, biochemistry, and cell biology work within the FEMTOMICS project.
  • Optimisation and validation of molecular biology, genomics, and biochemistry methods for investigating protein-DNA interactions.
  • Planning, conducting, and performing quality control of:
    • Cell culture experiments using adherent mammalian cell lines, including sample preparation for downstream next-generation sequencing (NGS), proteomics, and multiomics analyses;
    • Molecular biology, genomic, and biochemical experiments for the investigation of protein-DNA interactions;
    • NGS workflow, including sample and library preparation
  • Technical coordination of molecular biology work packages and coordination with interdisciplinary collaboration partners, core facilities, and external service providers.
Ihr Profil
  • A completed university degree at Master’s or Diploma level in biology, biochemistry, molecular biology, or a comparable natural science; a relevant doctorate is advantageous.
  • Demonstrated independent research experience acquired after completing a Master’s degree, with a suitable scientific and methodological profile.
  • Sound practical experience in several of the following areas: DNA and RNA analysis, (q)PCR, ChIP or related protein-DNA interaction methods, NGS library preparation, mammalian cell culture, ELISA, SDS-PAGE, Western blotting, immunoprecipitation, and binding assays.
  • Experience in independently planning, conducting, evaluating, and optimising scientific experiments and experimental workflows.
  • Strong analytical and independent scientific thinking, with the ability to critically evaluate experimental results, develop solutions to scientific and methodological challenges, and communicate findings effectively within an interdisciplinary research environment.
  • Practical experience with NGS methods is required. Knowledge of nanopore sequencing and sample preparation for LC-MS/MS analysis is advantageous.
  • Experience in bioinformatics using R, Python, or Bash and in the analysis or integration of proteomic and multiomics datasets is advantageous.
  • A demonstrated record of scientific publications is highly desirable.
  • Proficiency in using standard computer applications, such as Microsoft Office.
  • Very good English skills for scientific communication and laboratory work and very good German skills for handling administrative matters are expected.
Wir Bieten:

HAWK sees itself as a place that creates opportunities. We therefore expect the successful candidate to foster an equal-opportunity and diversity-oriented working environment in interactions with colleagues and students.

As a diversity-friendly university, we welcome employees with different backgrounds and particularly encourage applications from people from underrepresented groups. Our university supports the compatibility of family and career, among other things through highly flexible working-time models. The Equal Opportunities Office and the Staff Council will be happy to answer any related questions.

Applicants with severe disabilities will be given preferential consideration in accordance with the relevant statutory provisions if they have equal aptitude, qualifications and professional performance. To enable us to safeguard your interests, please indicate in your application whether you have a recognised severe disability or equivalent status.

Information pursuant to Article 13 GDPR on the collection of personal data can be found on our website at: https://www.hawk.de/datenschutz-stellenangebote.

Übersicht
  • Besoldungsgruppe E13 TV-L
  • Arbeitszeitanteil Vollzeit
  • Beschäftigungsart Wissenschaftliche Mitarbeit
  • Einstellungsdatum zum nächstmöglichen Zeitpunkt
  • Bewerbungsfrist 06.11.2026
  • Standort Göttingen
  • Hochschulorganisation Fakultät Ingenieurwissenschaften und Gesundheit
Ihre Ansprechperson für inhaltliche Fragen

For questions regarding the position, please contact Prof. Dr. Christoph Rußmann (christoph.russmann@hawk.de) or Nina Viessmann (nina.viessmann@hawk.de).

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