Research Associate for Structural biology and biochemistry § 28 Subsection 1 HmbHG

Hamburg Center for Health Economics; Hamburg; Vor Ort; EUR 40.000 - 60.000; Teilzeit

Zusammenfassung

A prestigious research institution in Hamburg is seeking a part-time Research Associate to conduct research on antibiotic resistance and engage in teaching. The ideal candidate will possess a relevant university degree and be experienced in biochemical methods. Responsibilities include utilizing structural biology techniques, particularly single particle cryo-EM. An attractive benefits package and work-life balance are provided.

Leistungen

Reliable remuneration based on wage agreements

Continuing education opportunities

Flexible working hours

30 days of vacation per annum

Health management

Qualifikationen

• University degree in a relevant field is required.
• Experience with biochemical and molecular biology methods is essential.
• Familiarity with single particle cryo-EM is advantageous.

Aufgaben

• Conduct research and teach at the university level.
• Investigate antibiotic interactions with the ribosome.
• Prepare complexes for cryo-EM analysis.

Kenntnisse

Biochemical methods

Molecular biology methods

PCR

Cloning

Protein expression

Protein purification

Ribosome analysis

Structural biology approaches

Single particle cryo-EM

Ausbildung

University degree in a relevant field

Jobbeschreibung

Institution

Faculty of Mathematics, Informatics and Natural Sciences, Department of Chemistry, Institute for Biochemistry and Molecularbiology

Salary level

EGR. 13 TV-L

Start date

01.02.2026, fixed for a period of three years. (This is a fixed-term contract in accordance with Section 2 of the academic fixed-term labor contract act [Wissenschaftszeitvertragsgesetz, WissZeitVG]).

Application deadline

30.11.2025

Scope of work

part‑time

Weekly hours

65 % of standard work hours per week

Your responsibilities

Research associates will be expected primarily to teach and conduct research. The research associate will also have the opportunity to pursue further academic qualifications, in particular a doctoral dissertation. At least one‑third of set working hours will be made available for the research associate’s own academic work.

The main goal is to understand how antibiotics inhibit the ribosome and protein synthesis and how bacteria obtain resistance to these classes of ribosome‑targeting antibiotics. To do this, the applicant will use biochemical approaches to form appropriate complexes between the antibiotics and the ribosome that can then be interrogated using structural biology approaches, such as single particle cryo‑EM. In addition, ribosome complexes will be formed with protein factors that confer antibiotic resistance or using ribosomes that contain mutations or modifications that confer antibiotic resistance. These complexes will then also be analyzed by single particle cryo‑EM approaches. Teaching hours 2,6.

Your profile

A university degree in a relevant field.

Experience with biochemical and molecular biology methods such as PCR, cloning, protein expression, and protein purification.

Experience with ribosomes, RNA and/or structural biology approaches, especially single particle cryo‑EM, would be an advantage.

We offer

• Reliable remuneration based on wage agreements
• Continuing education opportunities
• University pensions
• Attractive location
• Flexible working hours
• Work‑life balance opportunities
• Health management, EGYM Wellpass
• Educational leave
• 30 days of vacation per annum

The applicant will undergo training in sample preparation for cryo‑EM as well as data collection and processing methodologies for single particle cryo‑EM.

About University of Hamburg

Universität Hamburg—University of Excellence is one of the strongest research educational institutions in Germany. Our work in research, teaching, educational and knowledge exchange activities is fostering the next generation of responsible global citizens ready to tackle the global challenges facing us. Our guiding principle “Innovating and Cooperating for a Sustainable Future in a digital age” drives collaboration with academic and nonacademic partner institutions in the Hamburg Metropolitan Region and around the world. We would like to invite you to be part of our community to work with us in creating sustainable and digital change for a dynamic and pluralist society.

Equity statement

The University of Hamburg is committed to equity. Diversity enriches our university life, whether in our studies, research, teaching, education, or workplace. We therefore welcome all applications, regardless of gender, gender identity, sexual orientation, ethnic or social background, age, religion or belief, disability, or chronic illness. The University of Hamburg strives to increase the number of women in academia, and encourages qualified female academics to apply. Severely disabled and disabled applicants with the same status will receive preference over equally qualified non‑disabled applicants.

Instructions for applying

Contact

Prof. Dr. Daniel N. Wilson

[e-mail]

[phone]‑2841

Reference number: 303

Location: Martin‑Luther‑King‑Platz 6, 20146 Hamburg

Application deadline: 30.11.2025

Use only the online application form to submit your application with the following documents:

• cover letter
• CV
• copies of degree certificate(s)

If you experience technical problems, send an email to [e-mail].

More information on data protection in selection procedures.