Project Manager (f/m/d) – Gene Therapy Development

UMG; Göttingen; Hybrid; EUR 70.000 - 100.000; Vollzeit

Zusammenfassung

University Medical Center Göttingen (UMG) is seeking a Project Manager to coordinate a cross-disciplinary gene therapy development programme from discovery to clinical translation. The role combines science, manufacturing and regulatory planning, requiring strong leadership and clear communication across internal teams and external partners.

You will drive timelines, manage AAV/CMC activities, preclinical study plans and vendor contracts, and support regulatory interactions to advance a

Qualifikationen

• Must have MSc, PhD or equivalent in life sciences or related field.
• Proven experience in biotech/pharma development or translational research.
• Experience in project or programme management in a multidisciplinary development environment.
• Good understanding of biopharmaceutical development; gene therapy/viral vectors/ATMPs desirable.

Aufgaben

• Plan and coordinate cross-functional development activities and maintain the overall project plan, timelines and milestones.
• Coordinate AAV manufacturing and CMC activities, including process development, plasmid production, GMP manufacturing and analytical testing.
• Coordinate planning and execution of preclinical studies, including efficacy, safety, biodistribution and toxicology programmes with external CROs.
• Manage external partners and support vendor selection, contracting, project kick-offs and ongoing performance tracking.
• Support preparation for regulatory interactions and submissions, including Scientific Advice meetings.

Kenntnisse

Project management

Stakeholder management

Scientific/technical understanding

Organisational skills

Communication skills

Proactive mindset

Ausbildung

MSc/PhD in life sciences or related

Jobbeschreibung

Project Manager (f/m/d) – Gene Therapy Development

The interdisciplinary Institute for Auditory Neuroscience and the Else Kröner Fresenius Center for Optogenetic Therapies of the University Medical Center Göttingen aims to harness the great potential of optogenetics – the control of cells with light via light‑sensitive proteins – for clinical use. Optogenetic therapies combine gene therapy with optical medical devices, enabling broader applicability than traditional gene therapy and greater efficacy than current medical devices. The institute is developing an optical cochlear implant system aimed at restoring hearing in patients with severe‑to‑profound hearing loss.
We are looking for a Project Manager to join our interdisciplinary team and coordinate the development programme as we progress towards clinical translation.

• Planning and coordinating cross‑functional development activities and maintaining the overall project plan, timelines and milestones
• Coordinating AAV manufacturing and CMC activities, including process development, plasmid production, GMP manufacturing and analytical testing
• Coordinating planning and execution of preclinical studies, including efficacy, safety, biodistribution and toxicology programmes with external CROs
• Managing external partners and supporting vendor selection, contracting, project kick‑offs and ongoing performance tracking
• Supporting preparation for regulatory interactions and submissions, including Scientific Advice meetings

• MSc, PhD or equivalent degree in life sciences, biotechnology, pharmaceutical sciences, biomedical sciences or a related field
• Several years of experience in biotech, pharma, biopharmaceutical development or translational research
• Proven experience in project or programme management, ideally in a multidisciplinary development environment
• Good understanding of biopharmaceutical development; experience with gene therapy, viral vectors or ATMPs is highly desirable
• Strong organisational, communication and stakeholder‑management skills
• Ability to understand complex scientific and technical topics and translate them into actionable plans
• Proactive, structured and hands‑on working style, with a high level of ownership

We offer

• You will have the opportunity to play a key role in advancing a first‑in‑class optogenetic gene therapy towards clinical development, working at the interface of science, technology and regulatory development.
• As part of a small and highly interdisciplinary team, you will have significant ownership and direct impact on the development of a novel therapeutic approach.

The University Medical Center Göttingen (UMG) unites the Medical Faculty of the Georg‑August University and the University Hospital in an integration model. With around 9,700 employees, the UMG and its subsidiaries are one of the largest employers in the region. Our clinics and institutes stand for high‑quality patient care, excellent research, modern teaching and transfer of innovative technology.
Göttingen as a city of science is located in the center of Germany and the University Medical Center Göttingen is integrated into an attractive network of university and non‑university scientific institutions.

Our goal as University Medical Center Göttingen is professional equality for all genders. We strive to equalize the gender ratio in areas where there is underrepresentation. The University Medical Center Göttingen is particularly committed to the professional participation of severely disabled people and therefore welcomes applications from severely disabled people. In the case of equal suitability, applications from severely disabled persons will be given preferential consideration in accordance with the relevant regulations. We kindly ask you to indicate a disability/equal status in your letter of application in order to safeguard your interests.