Postdoctoral Scientist - assay development, Institute of Translational Medicine and Pharmacology

Universitätsklinikum Frankfurt; Frankfurt; Vor Ort; EUR 50.000 - 60.000; Vollzeit

Zusammenfassung

A major medical research institution in Frankfurt is seeking a Postdoctoral Scientist for assay development. Candidates should have a PhD in relevant fields and experience in assay development and cell biology. The role involves collaboration on advanced assay technologies with a competitive salary and professional development opportunities. Applications from women are especially encouraged.

Leistungen

Attractive salary based on TV-G-U, E13

Training for professional development

Health offerings including nutrition and exercise courses

Possibility for part-time employment

Free public transport in Hessen

Qualifikationen

• Experience in assay development and cell biology is essential.
• Proficiency in English required; German is a plus.

Aufgaben

• Conduct protein production and purification.
• Develop and apply biophysical/binding assays.
• Perform assay miniaturization and automation.
• Screen small-molecule compound libraries.
• Collaborate with data scientists on analysis.

Kenntnisse

Assay development

Cell biology

Independent problem solving

Data-driven experimental design

Proficiency in English

German language skills

Ausbildung

PhD in biology, biochemistry, molecular biology, cell biology, pharmacology

Jobbeschreibung

Postdoctoral Scientist – assay development, Institute of Translational Medicine and Pharmacology

Position type: Limited Contract, Full Time, 2-year appointment. Appointment, remuneration, and benefits based on TV‑G‑U.

The role is based in Frankfurt am Main at Goethe University Institute of Clinical Pharmacology. It is part of the Cluster4Future PROXIDRUGS, specifically the ProxiDETECT project, focused on advanced assay technologies for molecular glues and E3 ligase binders.

Responsibilities

• Protein production: cloning, expression in various systems, purification, quality control
• Development and application of biophysical/binding assays: thermal shift, surface plasmon resonance, biolayer interferometry, spectral shift, ligand displacement
• Assay miniaturization and automation
• Screening of medium-sized small‑molecule compound libraries
• Analysis of results in collaboration with data scientists, bioinformaticians, and chemoinformaticians

Qualifications

• PhD in biology, biochemistry, molecular biology, cell biology, pharmacology, or an equivalent field
• Experience in assay development and cell biology
• Independent problem solving, systematic, data‑driven experimental design and execution
• Proficiency in English required; German language skills are a plus

Benefits

• Attractive salary based on TV‑G‑U, E13, with annual special payment and company pension schemes
• Internal and external training for professional development
• Health offerings: online and face‑to‑face courses on nutrition, relaxation, sports and exercise
• Possibility for part‑time employment, childcare in daycare center, child care during holidays
• Free public transport in Hessen (Free State Ticket Hessen)
• Campus amenities: Uniklinik‑Campus, Mensa, cafés

Legal Requirements

Valid proof of measles immunity/vaccination is required.

EEO Statement

We welcome applications from candidates of all genders. Women are currently underrepresented in these positions at Universitätsmedizin Frankfurt. Therefore, applications from women are especially encouraged. Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.

Contact

Prof. Dr. Aimo Kannt – Email: [e-mail]

Application Procedure

Formal applications should consist of a single PDF document including cover/motivation letter and CV (with contact data for 2–3 referees). Please apply via the “Jetzt bewerben” button. The deadline is 24.11.2025.