Postdoctoral Scientist - assay development, Institute of Translational Medicine and Pharmacology

Universitätsmedizin Frankfurt; Frankfurt; Vor Ort; EUR 60.000 - 80.000; Vollzeit

Zusammenfassung

A prominent medical institution in Frankfurt is searching for a postdoctoral researcher to develop innovative therapies through assay development and drug discovery. Candidates must hold a PhD in relevant fields and demonstrate skills in teamwork and problem-solving. This role offers attractive benefits, including a competitive salary and the possibility of part-time work.

Leistungen

Attractive salary based on collective agreement

Training for professional development

Health offers and wellness courses

Childcare services

Free public transport in Hessen

Qualifikationen

• Experience in assay development and cell biology.
• Valid proof of measles immunity/vaccination required.

Aufgaben

• Protein production including cloning, expression, purification.
• Development of biophysical/binding assays.
• Screening small-molecule compound libraries.
• Collaboration with data scientists and bioinformaticians.

Kenntnisse

Independent problem solving

Data-driven experimental design

Proficiency in English

Teamwork in multidisciplinary environments

Ausbildung

PhD in life sciences

Jobbeschreibung

...you're in the middle of it The project is a close collaboration between Goethe University and the Fraunhofer Institute of Translational Medicine and Pharmacology (ITMP) in Frankfurt and Hamburg. The position will be based in Frankfurt am Main, at the Institute of Clinical Pharmacology, Goethe University. The position is limited to 2 years. Appointment, remuneration, and social benefits are based on the public-sector collective agreement (TV-G-U).

We invite applications for a postdoctoral researcher position in the field of assay development, drug discovery, and characterization within the Cluster4Future PROXIDRUGS (https://proxidrugs.de/en) project ProxiDETECT.

The Cluster4Future PROXIDRUGS aims to develop innovative therapies for human diseases by targeted degradation of disease-relevant proteins within cells. The cluster pools the expertise of several local universities, scientific institutes, and major pharmaceutical companies. Within PROXIDRUGS, the ProxiDETECT project develops advanced assay technologies and imaging solutions for the identification, biophysical and phenotypic characterization of molecular glues and novel ubiquitin E3 ligase binders. For this position, we are seeking an enthusiastic and ambitious candidate with a PhD in biology, biochemistry, molecular biology, cell biology, or a related field, with experience in assay development and cell biology.

Responsibilities

• Protein production (cloning, expression in various systems, purification, quality control)
• Development and application of biophysical/binding assays using different techniques (thermal shift, surface plasmon resonance, biolayer interferometry, spectral shift, ligand displacement)
• Assay miniaturization and automation
• Screening of medium-sized small-molecule compound libraries
• Analysis of results in close collaboration with data scientists, bioinformaticians, and chemoinformaticians

Skills we’re looking for

• PhD in life sciences, in biology, biochemistry, molecular biology, cell biology, pharmacology, or an equivalent field
• Skills in independent problem solving and systematic, data-driven experimental design and execution
• Proficiency in English required; German language skills are a plus
• You enjoy working in a multidisciplinary team
• Due to legal regulations, valid proof of measles immunity / measles vaccination is required

What we offer

• In addition to an attractive salary based on a collective agreement (TV-G-U, E13) with an annual special payment, you benefit from long-term security through company pension schemes
• Internal and external training for your professional development
• Benefit from our attractive health offers. We offer regular online and face-to-face courses on nutrition, relaxation, sports and exercise
• Part-time employment is possible, we offer childcare in our daycare center (if you have any questions, please contact UKF-Familienservice), child care during holidays
• Free public transport in all Hessen (Free State Ticket Hessen)
• Uniklinik-Campus, Mensa, Cafés
• Insights: Instagram, YouTube, LinkedIn
• FAQ's for new employees

Join Our Team!

Contact: Prof. Dr. Aimo Kannt
Email: [e-mail]
Formal applications consisting of one pdf document including a cover/motivation letter and CV (including contact data for 2-3 referees)
Application Deadline: 24.11.2025

We welcome applications from candidates of all genders. Women are currently underrepresented in these positions at Universitätsmedizin Frankfurt. Therefore, applications from women are especially encouraged. Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.