Postdoctoral Research Associate - Epidemiology and Cancer Control

ALSAC; Berlin; On-site; EUR 53,000 - 76,000; Full time

Benefits offered by this job

Competitive salary

Excellent benefits

Equal opportunity employer

Job summary

St. Jude Children’s Research Hospital is seeking a Postdoctoral Research Fellow to join the laboratory of Dr. Yadav Sapkota.

The role will focus on pharmacogenomics of long-term toxicities of cancer therapy in childhood survivors, with access to large-scale sequencing, multi-omics data, and deep phenotyping across time-points. The successful candidate will gain extensive training in genetic epidemiology, pharmacogenomics, and computational biology within a diverse, collaborative environment and

Qualifications

• PhD or equivalent degree in genetics, epidemiology, biostatistics, bioinformatics, or a related quantitative field.
• Strong publication record.
• Experience in statistical and computational analyses of high-throughput omics data.
• Ability to code in R, Python, C/C++.
• Excellent communication and writing skills.

Responsibilities

• Conduct genetic association analyses (WGS/WES, PRS) for cancer survivor health outcomes.
• Integrate multi-omics and system genetics data to elucidate molecular mechanisms.
• Collaborate with diverse teams and contribute to grant writing and dissemination.

Skills

Genetic epidemiology

Pharmacogenomics

Statistical genetics

Population genetics

Omics data analysis

R

Python

C/C++

Scientific writing

Education

PhD in genetics/epidemiology/biostatistics/bioinformatics

Job description

The Department of Epidemiology and Cancer Control is seeking a highly motivated Postdoctoral Research Fellow to join the laboratory of Dr. Yadav Sapkota. Successful candidates will work on projects related to pharmacogenomics of long-term toxicities of cancer therapy in childhood cancer survivors. This is a grant-funded position.

Specific research topics for this role include 1) genetic association analyses (whole genome and whole exome sequence associations and polygenic risk scores) for various long-term health outcomes among survivors of European and African ancestries; 2) analyses of multi-omics (genomics, transcriptomics, proteomics, and metabolomics) and system genetics (e.g., eQTLs regulating molecular responses to cancer therapies in human induced pluripotent stem cells) data for elucidating molecular mechanisms for health outcomes; and 3) evaluating health disparities through pharmacogenomics.

The candidate will have ample, immediate opportunities to work with large-scale whole genome and whole exome sequencing, RNA-seq, ATAC-seq, proteomics, and metabolomics data in a well-established cohort of childhood cancer survivors with clinically ascertained deep phenotyping of health outcomes at multiple time-points. S/he will work within a diverse, highly collaborative, and multi-disciplinary research environment and interact with world leaders in the fields of cancer survivorship, genetics, stem cell pharmacogenomics, epidemiology, biostatistics, and computational biology. The successful applicant will gain extensive training and experience in genetic epidemiology and pharmacogenomics, and computational and analytical skills with full access to cutting-edge tools/technologies and shared core facilities and resources. Grant-writing training opportunities and support are also available.

St Jude Children’s Research Hospital offers competitive salary, excellent benefits, and is an equal opportunity employer. To find more about our benefits for postdocs, click here.

Position qualifications:

• PhD or equivalent degree in genetics, epidemiology, biostatistics, bioinformatics, or a related quantitative field
• Strong publication record
• Strong research interests in genetic epidemiology, pharmacogenomics, statistical genetics, or population genetics and experience in statistical and computational analyses of high-throughput omics data
• Ability to code in one or more scientific programming languages (e.g., R, Python, C/C++)
• Excellent communication and writing skills

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St. Jude is an Equal Opportunity Employer

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