PHD/Department of Neurology/BBIM/DM/MH

Universit; Münster; Vor Ort; EUR 23.000 - 28.000; Vollzeit

Zusammenfassung

The University Hospital Münster invites applications for a Doctoral student (PhD student) position in computational biology, focusing on single-cell biology and neuroimmunology. The candidate will work in the Department of Neurology, using single-cell and spatial transcriptomics to study immune mechanisms in brain borders and peripheral nerves. The role is based in an international team led by Prof.

Dr. Meyer zu Hörste and supervised by PD Dr. Heming.

Qualifikationen

• Master’s degree in biology, biotechnology, bioinformatics, computational biology, or related field
• Strong analytical skills and ability to work independently and in teams
• Organisational skills, responsibility, reliability, and flexibility
• Proficiency in R and/or Python; familiarity with bioinformatics tools and single-cell/spatial data is a plus
• Hands-on experience with molecular biology and sequencing techniques

Aufgaben

• Investigate immune mechanisms at brain borders and peripheral nerves using single-cell and spatial transcriptomics
• Join interdisciplinary, international team led by Prof. Dr. Meyer zu Hörste and supervise by PD Dr. Heming
• Work with patient-derived samples and cutting-edge single-cell sequencing technologies
• Contribute to multi-omics projects characterising the single-cell landscape of neurological diseases

Kenntnisse

R

Python

Bioinformatics

Single-cell data

Analytics

Ausbildung

Master’s degree in biology/biotechnology/computational biology

Tools

Spatial transcriptomics

Sequencing techniques

Jobbeschreibung

The University Hospital of Münster is one of the leading hospitals in Germany. Such a position cannot be achieved through size and medical achievements alone. Above all, it is individual commitment that counts. We need your commitment so that we can achieve great things for our patients and for research. We offer you countless opportunities for personal and professional growth.

We have a clear social mission and, with our focus on healthcare, research, and teaching, we bear a unique responsibility.

To support our high standards in healthcare, research, and teaching, the Department of Neurology (Chair: Prof. Dr. Dr. S. Meuth) is seeking a highly qualified candidate for the following position:

Doctoral student (PhD student) position (m/f/d) in computational biology, with a focus on single-cell biology and neuroimmunology

Remuneration according to TV-L E 13 (65%)

Fixed-term appointment: 3 years

We are seeking a PhD candidate to join our interdisciplinary and international team. The successful candidate will investigate immune mechanisms at brain borders and in peripheral nerves using single-cell and spatial transcriptomics. The position is based in the renowned research group of Prof. Dr. Meyer zu Hörste at the Department of Neurology and will be supervised by PD Dr. Heming, a clinician scientist with a focus on single cell analysis and neuroimmunology.

The research groups led PD Dr. Heming and Prof. Dr. Meyer zu Hörste at the Department of Neurology combines patient-derived samples with cutting-edge single-cell and spatial transcriptomics to advance our understanding of human neurological diseases. Recent projects have used multi-omics approaches to characterise the single-cell landscape of human polyneuropathies (PubMed ID: 40849297) and identify progenitor B cells in the meninges (PubMed ID: 34253922). More information is available at mheming.com and https://www.medizin.uni-muenster.de/en/neurologie/forschung/mzh-lab.html .

Requirements

• A Master’s degree (or equivalent) in biology, biotechnology, bioinformatics, computational biology, or a related field
• Strong analytical skills and the ability to work both independently and collaboratively
• A strong sense of responsibility, excellent organisational skills, reliability, and flexibility
• A commitment to scientific rigour and enthusiasm for interdisciplinary research
• Proficiency in R and/or Python
• Familiarity with bioinformatics tools; experience analysing single-cell RNA sequencing or spatial transcriptomics data is an advantage
• Hands-on experience with molecular biology and sequencing techniques

We offer

• A highly motivated, international research team
• A collaborative and interdisciplinary research environment
• Access to state-of-the-art technologies, including single-cell sequencing and spatial transcriptomics platforms
• A unique opportunity to contribute to innovative research with clinical and translational relevance

When candidates are equally qualified, women will be given preference in accordance with applicable legal provisions. When candidates are equally qualified, applicants with a severe disability will be given preference.

Equal Opportunities

Equal opportunities are an integral part of our HR policy. UKM supports the compatibility of career and family life and has been certified as a family-conscious employer since 2010. In principle, part-time employment is possible. In areas where women are underrepresented, they will be given preferential consideration in accordance with statutory provisions, provided they have equal qualifications, aptitude, and professional performance. Applicants with severe disabilities will also be given preferential consideration under the same conditions and within the framework of legal regulations.

Further Information

• Due to the legal requirements of the German Measles Protection Act, employment with us is only possible with full vaccination protection against measles.
  
• We reserve the right to close the selection process as soon as a suitable candidate has been found.
  
• Applications submitted by email or post cannot be considered.
  
• Salary according to TV-L. Classification is based on the assigned responsibilities and qualifications. Placement within the pay scale levels is determined according to relevant professional experience.