Doctoral Position: Gene Expression Regulation (f/m/x)

University of Cologne; Deutschland; Vor Ort; EUR 52.000 - 60.000; Teilzeit

Benefits dieser Stelle

International team and collaborations

Flexible working time models

Advanced training opportunities

Equal opportunities

Zusammenfassung

University of Cologne invites applications for a part-time Doctoral Position in Gene Expression Regulation. The Uhlirova Lab at the Institute for Genetics within CECAD seeks a motivated candidate to lead an independent project in transcription, splicing, and spliceosome function, with exposure to multi-omics and cutting-edge methods.

The position is 25.89 hours per week for three years, with pay group TV-L 13 in the German public sector.

Jobbeschreibung

Organisation/Company University of Cologne Department Institute for Genetics | CECAD Research Field Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Application Deadline 27 Sep 2026 - 23:59 (Europe/Berlin) Country Germany Type of Contract Temporary Job Status Part-time Hours Per Week 25,89 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Reference Number Wiss2608-13 Is the Job related to staff position within a Research Infrastructure? No

Offer Description

Faculty of Mathematics and Natural Sciences
Doctoral Position: Gene Expression Regulation (f/m/x)
Uhlirova Lab | Institute for Genetics | CECAD

We are one of the largest and oldest universities in Europe and one of the most important employers in our region. Our broad range of subjects, the dynamic
development of our main research areas and our central location in Cologne make us attractive for students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration.

The Uhlirova lab ( www.uni-koeln.de/inter-fak/cecad/uhlirova/ ) explores how stress-inducible signaling pathways control gene expression and influence tissue
homeostasis and longevity. To tackle these questions, we combine the power of functional genetics in Drosophila and mouse models with cutting-edge molecular and cell biology, multi-omics approaches, advanced microscopy, and bioinformatics. We are looking for a highly motivated and curious doctoral candidate (f/m/x) to join our dynamic team. You will have the opportunity to lead your own project, contribute to collaborative research, and develop skills at the interface of
genetics, molecular and cell biology, and systems-level analysis.

YOUR TASKS

• To study the crosstalk between transcription and pre-mRNA splicing under physiological, stress, and disease conditions
• To investigate mechanisms underlying spliceosome assembly and functional plasticity
• To uncover what renders different transcripts, cells, and tissues sensitive to aberrant splicing
• To investigate how spliceosome malfunction contributes to loss of tissue homeostasis, premature aging and diseases

YOUR PROFILE

• Completed Master‘s degree or equivalent in Biology / Biochemistry/ Biophysics or related areas of Life Sciences
• Strong background in genetics, molecular and cell biology is essential
• Motivation, curiosity and creativity, and a strong ability to solve problems through critical analytical thinking
• Proven ability to carry out an independent scientific project and unwavering commitment to high-quality research
• Hands-on experience in working with model organisms, preferably Drosophila and/or mouse and cell culture systems
• Excellent communication skills, fluency in spoken and written English
• Strong commitment to collaboration and teamwork

DESIRED ASSETS

• Hands-on experience in multi-omics research projects and data analysis
• Experience with protein purification and biomolecular interaction assays
• Interest in computational modeling of biomolecular interactions
• Experience in quantitative image analysis and attention to detail
• Strong organizational and thorough documentation skills

WE OFFER

• Interactive and international team with access to state-of-the-art research facilities
• A diverse working environment with equal opportunities
• Support in balancing work and family life
• Extensive advanced training opportunities
• Occupational health management offers
• Flexible working time models

The University of Cologne promotes equal opportunities and diversity. Women will be considered preferentially in accordance with the Equal Opportunities Act of North Rhine-Westphalia (Landesgleichstellungsgesetz – LGG NRW). We also expressly welcome applications from all suitable candidates regardless of their gender, nationality, ethnic and social origin, religion, disability, age, sexual orientation and identity.

The position is available from immediately on a part-time basis (25,89 hours per week).The position is to be filled for three years. If the applicant meets the relevant wage requirements and personal qualifications, the salary is based on remuneration group 13 TV-L of the pay scale for the German public sector.

Number of offers available 1 Company/Institute Faculty of Mathematics and Natural Sciences Country Germany State/Province NRW City Cologne Geofield