Scientist: Cell Engineering & Phenotypic Screening

F. Hoffmann-La Roche AG; Basel; Vor Ort; CHF 140.000 - 190.000; Vollzeit

Zusammenfassung

F. Hoffmann-La Roche AG in Basel seeks a scientist to design and optimize cellular models powering phenotypic screening and drug discovery. You will apply CRISPR/Cas, generate stable cell lines, and enable scalable workflows for high-content imaging.

PhD in cell biology or related field required; strong communication in English and collaboration across teams are essential. This is a 100% lab-based role in a leading pharmaceutical research setting.

Qualifikationen

• PhD in cell biology, molecular biology, or closely related discipline.
• Postdoctoral or industry research experience is a plus but not required.
• Strong hands-on experience with advanced cell culture and genome editing.

Aufgaben

• Design and optimize disease-relevant cellular models at scale for phenotypic screening.
• Apply CRISPR/Cas and other methods to build robust assay systems.
• Translate models into scalable workflows for high-content imaging and screening.
• Collaborate with automation, data analysis, and chemistry teams to drive decisions.
• Foster an inclusive, collaborative lab culture focused on scientific innovation.

Kenntnisse

CRISPR/Cas genome editing

Stable cell line generation

NGS genotyping

iPSC differentiation

Molecular cloning

Transfection / viral transduction

High-content imaging

Multiparametric data analysis

English communication

Ausbildung

PhD in cell biology or related field

Tools

NGS platforms

CRISPR design tools

Jobbeschreibung

F. Hoffmann-La Roche AG in Basel seeks a scientist to design and optimize cellular models powering phenotypic screening and drug discovery. You will apply CRISPR/Cas, generate stable cell lines, and enable scalable workflows for high-content imaging.

PhD in cell biology or related field required; strong communication in English and collaboration across teams are essential. This is a 100% lab-based role in a leading pharmaceutical research setting.