Principal Clinical Scientist

W Talent Switzerland; Zürich; Vor Ort; EUR 90’000 - 130’000; Vollzeit

Zusammenfassung

A leading biopharmaceutical company in Switzerland seeks a Principal Clinical Scientist to lead early-stage clinical trials. This role involves identifying biomarkers, developing clinical strategies, and staying updated on neuroscience advancements. Ideal candidates will have a PhD or MD with extensive experience in CNS disorders, a collaborative mindset, and a strong passion for innovative drug development.

Qualifikationen

• 5+ years in pharmaceutical or biotech industry focusing on early-stage CNS drug development.
• Experience in overseeing drug development projects.

Aufgaben

• Drive early-stage clinical portfolio and clinical strategy.
• Collaborate on regulatory documents and scientific publications.

Kenntnisse

Extensive knowledge of CNS disorders

Strong understanding of clinical pharmacology

Organizational abilities

Negotiation skills

Strategic thinking

Fluency in English

Ausbildung

PhD in Neuroscience, Neuropharmacology or related field

M.D. with experience in neuropsychiatric conditions

Jobbeschreibung

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We are a clinical-stage biopharmaceutical company focused on advancing innovative treatments for complex neurological and psychiatric conditions. Our mission is to develop novel therapies that address unmet medical needs through cutting-edge scientific approaches.

We are seeking a Principal Clinical Scientist to drive the early-stage clinical portfolio and contribute to the design and execution of our clinical strategy.

Key Responsibilities

• Provide scientific and clinical expertise to identify and implement surrogate biomarkers and endpoints that demonstrate pharmacological activity in early-phase patient studies.
• Offer insights into preclinical models and pharmacodynamic measures translatable to humans, ensuring predictive value for clinical outcomes.
• Support the development and execution of clinical strategies for early-stage programs, including experimental medicine and Phase 1b/2 trials.
• Assist in evaluating and selecting traditional and novel clinical endpoints and biomarkers (e.g., biochemical, electrophysiological, molecular, imaging, or other relevant technologies) for use in experimental medicine frameworks.
• Collaborate with internal and external teams to prepare and submit regulatory documents (e.g., Investigator’s Brochure, IND, CTA).
• Contribute to drafting grant proposals and scientific publications alongside team members and external partners.
• Stay current on advancements in neuroscience, including scientific literature, clinical trials, competitive landscapes, and industry collaborations relevant to the company’s focus.

Qualifications and Skills

• Extensive knowledge of central nervous system disorders, with a PhD in Neuroscience, Neuropharmacology, or a related field, and/or an M.D. with experience in developing treatments for anxiety disorders, movement disorders, or other neuropsychiatric conditions.
• In-depth expertise in neuroscience or neuropharmacology, with at least 5 years of experience in the pharmaceutical or biotech industry, focusing on early-stage CNS drug development.
• Strong understanding of clinical pharmacology principles and regulatory requirements for designing and conducting successful early-phase clinical studies.
• Experience in planning, managing, and overseeing drug development projects and activities.
• Proven ability to thrive in cross-functional project teams, coordinating tasks under tight timelines and high workloads.
• Exceptional organizational, negotiation, and strategic-thinking abilities.
• Fluency in written and spoken English is essential.

Candidate Profile

We are looking for a highly motivated, resilient, and collaborative individual with a passion for solving complex challenges in novel drug development. If you thrive in a dynamic, fast-paced biotech environment, excel in multidisciplinary teams, and are driven to advance innovative therapies for neuropsychiatric disorders, we encourage you to apply.

Seniority level

• Seniority level

  Associate

Employment type

• Employment type

  Full-time

Job function

• Job function

  Science, Health Care Provider, and Research

• Industries

  Pharmaceutical Manufacturing and Biotechnology Research

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