PostDoc Position in Gastroenterology / Mucosal Immunology

University of Basel; Basel; Vor Ort; CHF 60’000 - 100’000; Vollzeit

Zusammenfassung

An innovative research group at a prestigious institution is seeking a dedicated scientist to explore mucosal immunology. This exciting role involves investigating immune responses to the intestinal microbiota, focusing on conditions like eosinophilic esophagitis and inflammatory bowel disease. The successful candidate will engage in cutting-edge research, employing techniques such as single-cell RNA sequencing and organoid generation. With a supportive environment and careful training, this position offers a unique opportunity to contribute to impactful research while collaborating with a dynamic team. Join us in advancing our understanding of the immune system and its interactions with food-derived antigens.

Qualifikationen

• PhD in Immunology or related field required.
• Experience with immunological techniques and molecular biology essential.

Aufgaben

• Plan and design experiments, including mouse experimentation.
• Carry out cell isolation, flow cytometry, and RNA isolation.

Kenntnisse

Mucosal Immunology

Cell Isolation

Flow Cytometry

RNA Isolation

qPCR

Immunohistochemistry

Immunofluorescence

Single-cell RNA Sequencing

Organoid Generation

Team Collaboration

Ausbildung

PhD in Immunology or related field

Tools

Flow Cytometer

RNA Sequencer

Jobbeschreibung

The research group “Gastroenterology" under the guidance of Prof. Jan Niess at the Department of Biomedicine, University of Basel, Basel, Switzerland, is looking for a scientist interested in mucosal immunology. Our research focuses on investigations designed to study immune responses to the intestinal microbiota and their products leading to intestinal diseases, such as eosinophilic esophagitis and inflammatory bowel disease. Particularly, we will study how food-derived antigens are recognized by the esophageal immune system and initiate eosinophilic esophagitis. The starting day will be February 2024.

• Planning and design of experiments, including mouse experimentation
• Carrying out cell isolation from the spleen and intestine, flow cytometry, RNA isolation and qPCR, immunohistochemistry, and immunofluorescence
• Single-cell RNA sequencing
• Generation of patient-derived organoids
• Experience in common immunological techniques and molecular biology
• Independence and being a team player in a research group
• Responsible and versatile tasks in a dynamic research group
• Careful training period and support by staff and research group leader