Mass Spec Research Intern: Drug Discovery Pathway

Philochem AG; Zürich; Vor Ort; CHF 22.000 - 29.000; Vollzeit

Zusammenfassung

Philochem AG in Otelfingen (near Zurich) invites applications for a Research Internship in Mass Spectrometry for Drug Discovery, with an Industrial PhD pathway. The role focuses on designing and validating an affinity-selection MS platform to identify novel ligands, collaborating with an interdisciplinary team to advance ligand-discovery programs.

The successful candidate will contribute to project work, including optimization of MS-based strategies, library generation, and data analysis, with a

Qualifikationen

• Master's degree in chemistry, medicinal chemistry, pharmacy, or related field required.
• Hands-on experience with HPLC and mass spectrometry instruments.
• Experience with organic synthesis (e.g., solid-phase) is advantageous.
• Understanding of drug discovery and development for small molecules.

Aufgaben

• Develop and optimize MS-based selection strategies and data-analysis workflows.
• Develop and implement synthetic workflows for library generation.
• Operate, troubleshoot, and maintain MS instrumentation (e.g., Orbitrap).
• Collaborate within interdisciplinary team and manage multiple activities.
• Present findings to project team and scientific meetings.
• Write and publish scientific articles in peer-reviewed journals.

Kenntnisse

Data analysis (R/Python)

Communication

Team collaboration

Proactive mindset

Ausbildung

Master's degree (MSc) in chemistry

Tools

Orbitrap mass spectrometers

HPLC systems

Xcalibur/OpenLab CDS

Mass-spec software (Skyline, MaxQuant, FragPipe)

Jobbeschreibung

Philochem AG in Otelfingen (near Zurich) invites applications for a Research Internship in Mass Spectrometry for Drug Discovery, with an Industrial PhD pathway. The role focuses on designing and validating an affinity-selection MS platform to identify novel ligands, collaborating with an interdisciplinary team to advance ligand-discovery programs.

The successful candidate will contribute to project work, including optimization of MS-based strategies, library generation, and data analysis, with a