DNA-Encoded Library Research Internship - Industrial PhD Pathway

Philochem AG; Zürich; Vor Ort; CHF 18.000 - 27.000; Vollzeit

Benefits dieser Stelle

Mentorship from experienced scientists

International biotechnology setting

Potential PhD pathway

Zusammenfassung

Philochem AG in Switzerland seeks an early-career scientist for a Research Internship in Drug Discovery and Development with an Industrial PhD Pathway. The role focuses on DNA-encoded libraries design, synthesis, screening, and validation to identify novel ligands for targeted therapies and diagnostics.

Strong collaboration across chemistry, biology, and MS is required. The internship offers hands-on experience and potential path to an industrial PhD with a leading European university, with a

Qualifikationen

• Master's degree in chemistry or a related field.
• Exposure to modern drug discovery concepts and translational research.
• Experience in synthetic chemistry or screening DELs is advantageous.
• Ability to interpret experiments with scientific rigor.
• Proactive, reliable, well-organized and responsible.
• Fluent written and spoken English.

Aufgaben

• Design and synthesize DNA-Encoded Chemical Libraries and related compounds.
• Screen libraries against pharmaceutically relevant targets.
• Validate hits using biochemical, biophysical, analytical, and cell-based assays.
• Analyze data and contribute to structure-activity relationships.
• Collaborate with chemistry, biology, and mass spectrometry teams.
• Present results and contribute to publications and IP.

Kenntnisse

Synthetic chemistry

Screening technologies

DNA-encoded libraries

Analytical methods

Data analysis

Interdisciplinary collaboration

Ausbildung

Master's degree in chemistry or related field

Tools

Mass spectrometry

Analytical instrumentation

Jobbeschreibung

Philochem AG in Switzerland seeks an early-career scientist for a Research Internship in Drug Discovery and Development with an Industrial PhD Pathway. The role focuses on DNA-encoded libraries design, synthesis, screening, and validation to identify novel ligands for targeted therapies and diagnostics.

Strong collaboration across chemistry, biology, and MS is required. The internship offers hands-on experience and potential path to an industrial PhD with a leading European university, with a