In Vivo Genome Editing Researcher — Mouse Models

University of Zurich; Zürich; Vor Ort; CHF 70.000 - 100.000; Vollzeit

Zusammenfassung

The University of Zurich seeks a skilled researcher to plan, coordinate and conduct in vivo studies in mouse models of genetic liver disease for clinical trial initiation. You will administer genome-editing therapeutics and perform animal monitoring, blood/tissue collection, necropsies, and downstream processing.

You will also perform molecular biology experiments (DNA/RNA isolation, PCR/qPCR, cloning) and document results with attention to Swiss regulations, collaborating with teams across

Qualifikationen

• Hands-on experience conducting mouse experiments is essential.
• Strong proficiency in molecular and cellular biology techniques.
• Ability to organize and conduct experiments independently and document results.

Aufgaben

• Plan, coordinate and conduct in vivo studies in mouse models of genetic liver disease for clinical trial initiation.
• Administer genome-editing therapeutics and other test substances.
• Perform animal monitoring, blood and tissue collection, necropsies, organ harvesting and downstream sample processing.
• Perform molecular and cellular biology experiments (DNA/RNA isolation, PCR/qPCR, cloning, sequencing preparation).
• Analyse, interpret and document results; maintain compliant records under Swiss animal-welfare regulations.
• Collaborate with scientists and partners across several research projects.

Kenntnisse

Mouse handling

Molecular biology

Cell culture

PCR/qPCR

Dosing/injections

Experimental design

English communication

Ausbildung

BSc or MSc in molecular biology/biotechnology/biomedicine or related field

Jobbeschreibung

The University of Zurich seeks a skilled researcher to plan, coordinate and conduct in vivo studies in mouse models of genetic liver disease for clinical trial initiation. You will administer genome-editing therapeutics and perform animal monitoring, blood/tissue collection, necropsies, and downstream processing.

You will also perform molecular biology experiments (DNA/RNA isolation, PCR/qPCR, cloning) and document results with attention to Swiss regulations, collaborating with teams across