Global MSAT DP Pilot Plant Bioprocess Scientist/Engineer (Basel, permanent)

Roche Holding AG; Basel; Vor Ort; CHF 120.000 - 180.000; Vollzeit

Zusammenfassung

Roche Holding AG recherche un Bioprocess Scientist pour soutenir les activités MSAT DP dans le réseau pilote et industriel. Le rôle implique la conception d'expériences, l'évaluation de technologies et le transfert de procédés vers les sites internes et externes.

Le candidat idéal apporte une formation en génie chimique/biotechnologique et une expérience en développement et opérations, avec des capacités de collaboration et de communication démontrées.

Qualifikationen

• B.S./M.S. en génie chimique ou biotechnologique avec au moins 3 ans d'expérience dans l'industrie OU doctorat avec 0–2 ans d'expérience pertinente.
• Compétences pratiques et théoriques en développement de procédés et fabrication, compréhension du développement pharmaceutique.

Aufgaben

• Concevoir et réaliser des expériences en laboratoire/pilot plant pour soutenir l'amélioration des procédés et la mise en œuvre de nouvelles technologies.
• Documenter et analyser les données, préparer des documents techniques et des présentations orales, soutenir les soumissions réglementaires sanitaires.
• Participer à des projets d'amélioration inter-départements et soutenir l'installation et le démarrage de la pilot plant.

Kenntnisse

Process development

Manufacturing

Collaborative work

Communication skills

Ausbildung

B.S./M.S. en génie chimique ou biotechnologique

PhD (0-2 ans d'expérience) en pharma/biotechnologie

Jobbeschreibung

Chez Roche, vous pouvez être vous-même et être apprécié pour les qualités uniques que vous apportez. Notre culture encourage l'expression personnelle, le dialogue ouvert et les connexions authentiques, où vous êtes valorisé, accepté et respecté pour ce que vous êtes, vous permettant de prospérer tant personnellement que professionnellement. Voici comment nous visons à prévenir, arrêter et guérir les maladies et à garantir à chacun l'accès aux soins de santé aujourd'hui et pour les générations à venir. Rejoignez Roche, où chaque voix compte.

La position

As part of Pharma Technical Operations (PT), Pharma Technical Technology (PTT) plays a key role in leading a seamless industrialization and thorough technical product management through integrating SHE, proactive maintenance, facility fitness, performance optimization and scalable manufacturing processes and technologies in support of the manufacturing network. Product and process robustness, efficiency and reliability are key performance indicators, PTT owns and drives towards improvement.

Within PTT, Roche’s global Manufacturing Science and Technology (gMSAT) department is the process and product owner for our commercial products, including our internal and external drug substance and drug product network, implementation of new technologies, network standardization, and mitigation of technical risks.

The Global MSAT DP Pilot Plant Bioprocess Scientist, reporting to the Global MSAT DP Operations:

Lead design & executes experiments to support process and product improvements, technology implementation, process validation, hands-on second-level commercial product support and process transfer to & from internal manufacturing and contract manufacturing sites, as requested. This team is an execution-obsessed team focused on conducting experiments within our existing pilot plant network, accurately documenting and analyzing data, summarizing results in technical documents and oral presentations, and supporting health authority submissions and inquiries. This role may also support inter-departmental process, technology and business process improvement projects.

Supports to pilot plant establishment project. This role will support the design, implementation and operational start of the foreseen Pilot Plant. It will include support to implementation of equipments, establishment of procedures and all elements necessary to the start of a pilot plant

In this role you will maximize individual and collective contributions to deliver timely business results in support of PTT and PT goals. You will enable the network to solve process and technology driven operational challenges through data-driven insights and laboratory / pilot plant experimentation for internal and external manufacturing networks.

The Opportunity

• Interface with Technical Development and MSAT teams to design and execute lab-scale experiments within the MSAT laboratory/pilot plant

• Support Make-Assess-Release (MAR) activities in collaboration with MSAT and manufacturing as needed

• Document and analyze data, summarizing results in technical documents and oral presentations, and support health authority submissions

• Support or lead inter-departmental process, technology and business process improvement projects as needed

• Solves problems autonomously and adapts plans to address resource and operational challenges.

• Participate the project, implementation and operation of the Pilot plant

• Work on multiple projects, prioritizing effectively, and adapting to changes quickly

• Represent the function on cross-functional project teams, where they will collaborate with leads from other functions on all aspects of project deliverables

• Stay updated on industry trends and advancements in bioprocess technologies

• Collaborate with representatives from Development, Manufacturing, Quality, and Regulatory functions as required

• As required, review/author sections in regulatory submissions, as well as responses during Health Authority inquiries

• Serve as an ambassador for the function with the ability to influence stakeholders for new technology development and implementation

• Train and mentor team members to enhance their skills and promote professional growth

• Provide knowledge and training on complex process and equipment technologies to PT partners as required

Who you are

• Experience & Education: You have a B.S. or M.S. degree in Chemical, Biochemical Engineering, or related discipline with at least three years of experience in the industry OR a PhD with 0-2 years of of relevant experience in the pharmaceutical or biotechnology industry with process development, operations/manufacturing, or related experience

• Technical Expertise: Extensive practical and theoretical expertise in process development and manufacturing, with deep understanding of the drug development process

• Ability to build connections, encourage feedback, and foster a collaborative environment, strong written and verbal communications skills

• Committed to creating an inclusive environment where team members feel safe, valued, and empowered to perform their best.

• Ability to work independently and challenge the status quo, handle multiple projects, prioritize and delegate effectively, adapt to changes quickly, and work collaboratively on cross-functional teams

• <5% of travel required

Qui nous sommes

Un avenir plus sain nous pousse à innover. Ensemble, plus de 100 000 employés à travers le monde sont dédiés à faire progresser la science et à garantir à chacun l'accès aux soins de santé aujourd'hui et pour les générations à venir. Nos efforts aboutissent à plus de 26 millions de personnes traitées avec nos médicaments et plus de 30 milliards de tests réalisés avec nos produits de Diagnostique. Nous nous encourageons mutuellement à explorer de nouvelles possibilités, à favoriser la créativité et à conserver nos grandes ambitions, afin de fournir des solutions de santé qui changent des vies et ont un impact mondial.

Construisons ensemble un avenir plus sain.

Roche est un employeur offrant l'équité en matière d'emploi.