Research / Lab Assistant (80%) in Vivo Systems Neuroscience and Neurodegeneration

Athena's Journey; Montreal; On-site; CAD 81,000 - 115,000; Part time

Benefits offered by this job

2-year fixed-term position

Training in advanced in vivo neurotech

International collaborative lab

Job summary

The Department of Biomedicine at the University of Basel is seeking a motivated Research / Lab Assistant (80%) to join a project on tau pathology and neural circuit function in early Alzheimer's disease. The role involves in vivo mouse work, stereotaxic surgeries, chronic Neuropixels recordings, histology support, and animal welfare monitoring within an international, collaborative setting.

You will gain training in advanced electrophysiology and contribute to longitudinal studies in a dynamic

Qualifications

• 1 year hands-on experience with in vivo rodent experiments.
• Experience with rodent handling and welfare monitoring in a research setting.
• Stereotaxic surgery experience and good documentation practices.

Responsibilities

• Perform and support mouse experiments including surgeries, behavioural training, and chronic in vivo recordings.
• Support histology processing and sample preparation for ex vivo experiments.
• Monitor animals before, during, and after procedures and maintain accurate experimental records.

Skills

In vivo experiments

Rodent handling

Stereotaxic surgery

Behavioral training

Histology sample prep

Documentation

English communication

Education

Bachelor's/Master's in neuroscience or related

Tools

Neuropixels

Electrophysiology equipment

Job description

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance the understanding of health and disease.

We are home to more than 67 research groups and over 800 employees across six locations in the heart of Basel. Our collaborative and international environment fosters innovation, excellence, and impactful research.

The Brain Ageing and Neurodegeneration led by Prof. Marc Aurel Busche, is looking for a Research / Lab Assistant.

Join our community and help shape the future of biomedicine.

Your position

We are looking for a motivated and technically skilled Research / Lab Assistant (80%) to join a newly funded project investigating how tau pathology disrupts neural circuit function during the early stages of Alzheimer's disease.

The project combines mouse behaviour, chronic multi-region electrophysiological recordings (Neuropixels), viral approaches, and analysis of large-scale neural population activity to study how pathological changes in neural activity emerge and contribute to cognitive impairment.

• Perform and support experimental procedures in mice, including stereotaxic surgeries, behavioural training and testing and chronic in vivo electrophysiological recordings
• Support histological processing and sample preparation for ex vivo experiments
• Support the monitoring of animals before, during, and after experimental procedures

Your profile

• Valid certification to perform animal experiments in Switzerland (LTK1 or equivalent qualification)
• At least 1 year of hands-on experience with in vivo experiments in rodents, gained through a technical apprenticeship, veterinary technician training, or a Bachelor's/Master's degree in a relevant field
• Experience working with rodents in a research environment, including animal handling, welfare monitoring, and experimental documentation
• Experience with stereotaxic surgery in rodents
• Good communication skills in English

Preferred

• Experience with in vivo electrophysiology and/or neural recording techniques
• Experience with behavioural neuroscience experiments
• Ability to communicate in German is an advantage

We offer you

• A 2-year fixed-term position (80%)
• Training in advanced in vivo neuroscience techniques, including chronic Neuropixels recordings
• Opportunity to contribute to establishing new experimental workflows and longitudinal studies
• An international and collaborative research environment