Postdoctoral Position

Biomb; Winnipeg; Hybrid; CAD 55,000 - 65,000; Full time

Job summary

St. Boniface Hospital Research and the University of Manitoba invites applications for a two-year postdoctoral position in Neuroscience/Neuropharmacology.

The project, Using Sonogenetics to Replace Pharmaceuticals, will mobilize ultrasound to activate genetically modified ion channels to drive nerve repair and suppress pain, using neuronal cell lines and adult sensory neurons transduced with AAVs. PhD in neurobiology or related field required; experience in signal transduction, cell culture,

Qualifications

• Must hold a PhD in neurobiology or a related field (e.g., cell biology or pharmacology).
• Experience with signal transduction, cell culture, gene expression studies, genetic manipulation and/or fluorescence microscopy would be advantageous.

Responsibilities

• Postdoctoral research on sonogenetics to activate modified ion channels for nerve repair and pain suppression.

Skills

Signal transduction

Cell culture

Gene expression studies

Genetic manipulation

Fluorescence microscopy

Education

PhD in neurobiology or related field

Tools

AAV transduction

Job description

St. Boniface Hospital Research and the University of Manitoba

POSTDOCTORAL POSITION

Neuroscience/Neuropharmacology – 2 years

Project: Using Sonogenetics to Replace Pharmaceuticals

A US government-funded project will mobilize ultrasound to activate genetically modified ion channels to drive nerve repair and suppress pain. Neuronal cell lines and adult primary sensory neurons will be transduced with AAVs carrying sonochannels, which will be modulated by ultrasound to activate signalling pathways linked to neuronal metabolism and axonal regeneration.

For Dr. Paul Fernyhough’s lab history, see ORCid at https://orcid.org/0000-0002-9507-1201

Qualifications:Must hold a PhD in neurobiology or a related field (e.g. cell biology or pharmacology). Experience with signal transduction, cell culture, gene expression studies, genetic manipulation and/or fluorescence microscopy would be advantageous.

Salary: CA$55,000 – CA$65,000 per annum