Research Associate II: Protein Purification Specialist

Zymeworks Inc.; Vancouver; On-site; CAD 62,000 - 94,000; Full time

Benefits offered by this job

Vacation & PTO

Medical, dental & vision benefits

RRSP / 401K / Pension

Employee Share Purchase Program

Employee Equity Program

Volunteer time off

Job summary

Zymeworks Inc. is seeking a hands-on scientist to perform protein purification and analytical characterization within a fast-paced biotech setting in Vancouver, BC.

You will design experiments for multispecific antibody developability, contribute to affinity measurements, and help advance project milestones while adhering to OH&S and quality standards. The role requires a BSc (or MSc) in a relevant field and 2–3 years of related experience, with hands-on purification and analytical technique

Qualifications

• BSc in a relevant scientific discipline with 2–3 years of related experience or MSc with equivalent experience.
• Hands-on protein purification experience (affinity, protein A/G/L, IEX, SEC).
• Experience with protein analytical techniques (PAGE, CE-SDS, ELISA, MSD, UPLC-SEC).
• Knowledge of developability assays (AC-SINS, non-specific ELISA, HIC).
• Understanding affinity measurement methods (SPR, BLI, KinExA, on-cell binding).
• Ability to work in cross-functional teams and fast-paced environments.
• Strong data presentation and reporting skills.

Responsibilities

• Perform protein purification and analytical characterization of various protein-based molecules.
• Design and execute experiments to characterize multispecific antibody therapeutics through developability assays.
• Assist in affinity measurements to screen protein therapeutics.
• Troubleshoot methods and develop new technologies for project advancement.
• Write SOPs for technically complex methods.
• Analyze data and present findings to teams.
• Maintain a clean, organized lab and ensure OH&S compliance.
• Foster collaborative working relationships across the organization.

Skills

Protein purification

Analytical characterization

Developability assays

Cross-functional teamwork

Data presentation

Laboratory skills

OH&S compliance

Education

BSc in Biochemistry / related field

Master’s degree (optional)

Tools

SPR

BLI

KinExA

ELISA

Job description

Zymeworks Inc. is seeking a hands-on scientist to perform protein purification and analytical characterization within a fast-paced biotech setting in Vancouver, BC.

You will design experiments for multispecific antibody developability, contribute to affinity measurements, and help advance project milestones while adhering to OH&S and quality standards. The role requires a BSc (or MSc) in a relevant field and 2–3 years of related experience, with hands-on purification and analytical technique