Evidence Operations Manager

F. Hoffmann-La Roche AG; Mississauga; On-site; CAD 106,000 - 139,000; Full time

Job summary

F. Hoffmann-La Roche AG in Canada seeks an Evidence Operations Manager to oversee operational execution of evidence-generation studies, including interventional and RWE activities, ensuring milestones are met on time and within budget.

You will manage trial operations, vendor relationships, and platform tracking, contributing strategic feasibility input and driving process improvements across cross-functional teams.

Qualifications

• Bachelor’s degree in a medical or science-related discipline required.
• Master’s degree in Science or Post-Graduate Diploma in Clinical Research preferred.
• Strong knowledge of ICH-GCP and regulatory frameworks.

Responsibilities

• End-to-End Operational Ownership: lead assigned evidence-generation studies and programs, delivering milestones on time and within budget.
• Trial Management & Platform Tracking: manage IMP, budgets, milestones, and real-time databases/tools.
• Vendor & Stakeholder Oversight: collaborate with sponsors, sites, and vendors to ensure quality, compliant deliverables.
• Strategic Input & Feasibility: provide operational input to Medical Affairs in conceptualization and conduct phases.
• Process Excellence & Innovation: improve workflows to enhance efficiency in clinical operations.
• Cross-Functional Collaboration: act as primary operational contact, maintaining strong internal/external relationships.

Skills

Project management

Stakeholder engagement

Clinical trial operations

Regulatory knowledge

Problem-solving

Communication

Education

Bachelor’s degree in a medical or science-related discipline

Master’s degree in Science or Post-Graduate Diploma in Clinical Research

Tools

MS Office

Google Workspace

Clinical data management systems

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position A healthier future. That’s what drives us.

Evidence Operations Manager (EOM)

EOM provides operational expertise and oversight to the Canadian affiliate's research portfolio to ensure the successful, timely execution of strategic, innovative evidence. The EOM oversees and manages the operational implementation of all supported studies (including Investigator Initiated Studies), Managed and Funded Non-Interventional Studies, Scientific Credibility and RWE studies in accordance with the applicable regulatory requirements and guidelines (e.g. AMG, MPG, ICH / GCP etc.) as well as applicable Roche SOPs. As a key partner with your therapeutic area team, you provide portfolio oversight and strategic insights to maximize the feasibility and impact of these activities.

The Opportunity

• End-to-End Operational Ownership: Lead assigned evidence-generation studies and programs, taking full accountability for delivering operational milestones on time, within budget, scope, and aligned with strategic objectives.
• Trial Management & Platform Tracking: Manage day-to-day operational elements—including IMP management, budget oversight, and key milestone tracking—ensuring trial management databases and tracking tools are maintained accurately in real time.
• Vendor & Stakeholder Oversight: Partner with external sponsors, research sites, and vendor partners to ensure quality deliverables that comply with agreed budgets, ICH-GCP standards, local regulations, and Roche SOPs while proactively identifying and mitigating risks.
• Strategic Input & Feasibility: Provide operational expertise to Medical Affairs strategy hubs during the conceptualization, feasibility, start-up, and conduct phases of evidence-generation activities.
• Process Excellence & Innovation: Continuously evaluate study workflows to identify efficiencies, solve complex operational challenges, and contribute to overall clinical operations excellence.
• Cross-Functional Collaboration: Serve as the primary operational point of contact for assigned studies, building and maintaining collaborative, high-trust relationships with internal and external stakeholders.

Who you are

• Education & Experience: Bachelor’s degree in a medical or science-related discipline required (Master’s degree in Science or Post-Graduate Diploma in Clinical Research preferred), with a minimum of 2–4 years of experience in clinical research (interventional trials or RWD/RWE) or the broader health industry.
• Project & Process Management: Demonstrated ability to manage complex projects, prioritize tasks effectively, and drive deliverables on target, on schedule, and within budget.
• Operational Expertise: Strong working knowledge of clinical trial management operations, including ICH-GCP standards and relevant regulatory frameworks.
• Agility & Problem-Solving: Highly organized, self-motivated, and results-oriented with a proven ability to navigate ambiguity, manage competing priorities, and implement solutions-focused approaches.
• Stakeholder Engagement & Communication: Exceptional customer focus with strong communication and presentation skills, capable of building collaborative working relationships across cross-functional teams.
• Preferred: High proficiency in English (written and spoken) is required; French language skills are considered a strong asset.
• Technical & AI Competency: Strong digital literacy with proficiency in MS Office, Google Workspace platforms, clinical data management systems, and an openness to leveraging emerging digital/AI tools to optimize workflows.
• Therapeutic Domain Knowledge: Familiarity with key therapeutic areas relevant to Roche’s portfolio.
• Project Management & Strategic Alignment: Advanced proficiency in strategic project oversight, with a proven track record of translating overarching medical goals into structured, execution-ready operational plans.
• Advanced Stakeholder Engagement: Proven ability to influence without direct authority, navigate difficult conversations effectively, lead complex negotiations, and consistently deliver an exceptional customer experience to internal and external partners.

This position is not eligible for relocation support.

The expected salary range for this position based on the primary location of Mississauga is 105,560.00 and 138,547.50 of hiring range. Actual pay will be determined based on experience, qualifications, and other job-related factors as determined by the company.

We use artificial intelligence to screen, assess or select applicants for this role. This posting is for an existing vacancy at Hoffmann-La Roche Ltd.

Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life‑changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.