Bioinformatics Scientist

Creative Solutions Services, LLC; Mississauga; On-site; CAD 70,000 - 95,000; Full time

Job summary

An established industry player is seeking a Bioinformatics Scientist to join their innovative team in Mississauga. This role involves collaborating with molecular biologists to enhance next-generation sequencing technologies and develop cutting-edge algorithms for cancer detection. The ideal candidate will have a strong background in bioinformatics, particularly in genomic data analysis, and will thrive in a dynamic, collaborative environment. Join this forward-thinking company and contribute to groundbreaking advancements in the field of oncology.

Qualifications

• Experience in high-throughput sequence analysis and bioinformatics.
• Proficient in Python and R programming languages.

Responsibilities

• Analyze bioinformatics data and troubleshoot pipelines.
• Collaborate with scientists to develop new assay methodologies.

Skills

Sequencing/Genomic Data Analysis

Bioinformatics Tools

Python

R

Linux HPC Environment

Workflow Management Systems

Communication Skills

Tools

Nextflow

Snakemake

JIRA

SQL

Docker

R Shiny App Development

Job description

Mississauga, ON, Canada All On-site Contract

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Job Description

Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, is focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Bioinformatics Scientist to support assay development efforts.

In this role, you will collaborate closely with molecular biologists and bioinformatics scientists and apply your strong knowledge in processing and analyzing next generation sequencing technologies. You will maintain, improve and develop internal algorithms, tools and pipelines for oncology applications (such as variant calling) as well as analyzing biological data for assay development

Responsibilities
• Provide hands-on bioinformatics data analyses and troubleshooting of bioinformatics pipelines
• Implement innovative algorithms for minimal residual disease and cancer early detection
• Collaborate with wet-lab scientists and bioinformaticians to develop new assay methodologies
• Work with external collaborators of Roche and provide bioinformatics support for them
• Present and communicate team activities/project results across multiple functions in the organization


Required Skills:
● Documented experience with sequencing/genomic data analysis (NGS), especially in the area of high-throughput sequence analysis
● Proficient in general bioinformatics tools including tools for sequence alignment, variant analysis, and database queries
● Proficient in Python and R
● Proficient working in a Linux HPC environment
● Hands-on experience in workflow management system (e.g. Nextflow, Snakemake)
● Working understanding of biological concepts and experimental methods commonly used in molecular biology and interest to learn more
● Excellent communication, advanced English reading, writing, listening and speaking skills; Responsible and reliable, goal and task oriented.

Preferred Skills:
● Strong statistical background
● Experience with version control and familiarity with issue tracking systems (i.e .JIRA).
● Familiarity with database languages such as SQL
● Experience with container-based virtualization (i.e. Docker)
● Familiarity with R Shiny App development
● Experience with immune repertoires data analysis

Note: The ideal candidate will work in the Mississauga office at least 2 days a week