Principal Clinical Scientist

Alignerr Corp.; Rio de Janeiro; Remote; BRL 517,000 - 886,000; Part time

Job summary

Alignerr is seeking a Principal Clinical Scientist (AI Training) to lead design and evaluation of clinical trial data used for training AI systems. This senior role requires deep regulatory experience and meticulous data scrutiny to ensure regulator-ready datasets.

You will audit results, validate AI-derived analyses, and provide structured feedback to improve AI reasoning about clinical evidence. The work is remote, flexible, and hourly, with 10–40 hours per week.

Qualifications

• Senior-level experience designing clinical trial protocols for regulatory submission.
• Deep expertise interpreting clinical data for agencies such as FDA/EMA or equivalents.
• Strong grounding in clinical research methodology or biostatistics.
• Naturally detail-oriented with a rigorous, systematic approach to evaluating evidence.
• Clear and precise written communicator able to articulate complex findings.

Responsibilities

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training.
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance.
• Evaluate AI-generated clinical analyses for scientific soundness and regulatory alignment.
• Provide expert, structured feedback that improves how AI models reason about clinical trial data.
• Work independently and asynchronously — fully on your own schedule.

Skills

Senior-level experience

Regulatory submissions

Biostatistics

Clinical trial design

Written communication

Job description

Principal Clinical Scientist (AI Training)

About The Role

What if your career-long expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about clinical evidence?

We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows. Your work will help ensure that the clinical data used to train and evaluate frontier AI systems meets the standards expected in real-world regulatory submissions — making AI smarter, safer, and more trustworthy in biomedical contexts.

This is a fully remote, flexible contract role. No AI background required — just deep clinical expertise and a sharp eye for scientific quality.

• Organization: Alignerr
• Type: Hourly Contract
• Location: Remote
• Commitment: 10–40 hours/week

What You'll Do

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with regulatory expectations
• Provide expert, structured feedback that improves how AI models reason about clinical trial data and outcomes
• Work independently and asynchronously — fully on your own schedule

Who You Are

• Senior-level experience designing clinical trial protocols for regulatory submission
• Deep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodies
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Naturally detail-oriented with a rigorous, systematic approach to evaluating scientific evidence
• Clear and precise written communicator — able to articulate complex findings in structured formats
• No prior AI or tech experience required

Nice to Have

• Prior experience with data annotation, data quality review, or evaluation systems
• Background in drug development, medical devices, or clinical operations
• Familiarity with AI tools or scientific evaluation workflows as an end user
• Experience in academic research, contract research organisations (CROs), or regulatory consulting

Why Join Us

• Work directly on frontier AI systems making an impact in clinical and biomedical research
• Influence how AI understands, evaluates, and reasons about real-world clinical evidence
• Fully remote and flexible — work when and where it suits you
• Freelance autonomy with the structure of meaningful, expert-level work
• Collaborate with leading AI research teams and labs at the cutting edge of the field
• Potential for ongoing work and contract extension as new projects launch