R&D Clinical Ops & Portfolio Strategy Lead

PwC; Brussel; Hybrid; EUR 90,000 - 130,000; Full time

Benefits offered by this job

Flexible hybrid work patterns

Lifelong learning

Flexible rewards

Sustainable mobility

Inclusive culture

Wellbeing focus

Global PwC network

Job summary

PwC Belgium is seeking a seasoned Senior Manager to join the Advisory team within the R&D & Quality group. You will lead complex clinical operations and portfolio governance engagements for Pharma and Life Sciences clients, shaping delivery and strategic outcomes.

The role requires deep knowledge of regulatory expectations (ICH GCP, EU CTR, FDA IND), a proven consulting background, and the ability to design operating models, support digital initiatives (CTMS, eTMF, RBQM) and mentor junior staff.

Qualifications

• 7–9 years of experience in clinical operations, portfolio strategy, or related roles within Pharma or Life Sciences.
• Proven consulting or advisory background.
• Master’s degree in Life Sciences, Pharmaceutical Sciences, Biomedical Engineering, or related discipline.
• Strong working knowledge of regulatory frameworks (ICH GCP, EU CTR, global).
• Experience in Clinical Operations Excellence, Portfolio Strategy & Governance, RBQM, Digital enablement (CTMS, eTMF, analytics).

Responsibilities

• Lead and deliver complex clinical operations and portfolio strategy engagements for Pharma and Life Sciences clients.
• Provide guidance on regulatory expectations and industry best practices.
• Design, implement, and optimize operating models for clinical trial execution and governance.
• Support digital initiatives (CTMS, eTMF, analytics) and portfolio decision-making.
• Mentor junior consultants and contribute to knowledge development.

Skills

Clinical Operations

Portfolio Strategy

Governance

RBQM

Digital enablement

Education

Life Sciences Masters

Pharmaceutical Sciences

Biomedical Engineering

Tools

Veeva Vault Clinical

Medidata

Planisware

Job description

PwC Belgium is seeking a seasoned Senior Manager to join the Advisory team within the R&D & Quality group. You will lead complex clinical operations and portfolio governance engagements for Pharma and Life Sciences clients, shaping delivery and strategic outcomes.

The role requires deep knowledge of regulatory expectations (ICH GCP, EU CTR, FDA IND), a proven consulting background, and the ability to design operating models, support digital initiatives (CTMS, eTMF, RBQM) and mentor junior staff.