Manager Biomanufacturing - Upstream

UCB; Eigenbrakel; Hybrid; EUR 110,000 - 150,000; Full time

Job summary

UCB in Belgium seeks a Biomanufacturing Manager - Upstream to lead operations at the Belgium Biomanufacturing Operations Center in Braine-L'Alleud. The role focuses on safe, compliant upstream production, people leadership, and continuous improvement in a regulated environment.

You will drive performance, mentor senior team members, and partner with cross-functional groups to deliver patient-focused medicines.

Qualifications

• Bachelor's or Master's degree in science, engineering, or related field.
• 10+ years in biopharmaceutical manufacturing.
• Experience leading production teams in a regulated environment (including executive-level staff).
• Strong knowledge of Good Manufacturing Practices and industrial production processes.
• Excellent communication, problem-solving and decision-making skills.

Responsibilities

• Oversee safe, compliant and efficient upstream biomanufacturing operations.
• Lead and develop team leaders and technicians, fostering collaboration and continuous improvement.
• Monitor production performance, analyse results and implement corrective actions.
• Coordinate with maintenance, qualification and calibration for equipment readiness.
• Manage deviations, investigations and CAPAs to ensure regulatory compliance.
• Drive continuous improvement initiatives and support audits and inspections.

Skills

Leadership

GMP knowledge

Upstream processes

Biopharmaceutical manufacturing

Executive-level staff leadership

Communication

Problem-solving

Decision-making

French

English

Education

Bachelor's or Master's degree in science, engineering

Job description

Location:

Braine L'alleud, Walloon Brabant, BE

Job Function: Manufacturing

Job ID: 93431

Make your mark for patients

We are looking for a talented and motivated Biomanufacturing Manager - Upstream to join our Belgium Biomanufacturing Operations Center in Braine-L'Alleud, Belgium.

Here, you will have the opportunity to truly expand your expertise in a dynamic and forward-looking environment where your growth and development are a priority. By working with the latest technologies and innovative techniques, you will help produce groundbreaking medicines that make a real difference for patients - today and in the future.

About the role:

You will be responsible for overseeing manufacturing operations within a biopharmaceutical production environment. You will ensure production runs efficiently, safely, and in compliance with regulatory standards while fostering continuous improvement and team development. You will play a key role in delivering production targets, maintaining quality standards, and building a strong, engaged team.

Who you'll work with:

You will be working in a team that collaborates closely with production teams, quality specialists, supply chain, technical services, and human resources. You will lead team leaders and technicians while partnering with cross-functional experts to ensure smooth, compliant, and efficient manufacturing operations.

What you'll do:

• Ensure safe, compliant, and efficient execution of manufacturing operations aligned with quality, safety, and production targets
• Lead and support team leaders and technicians, promoting collaboration, development, and continuous improvement
• Monitor production performance, analyze results, and implement corrective actions when needed
• Oversee equipment readiness with technical teams, including maintenance, qualification, and calibration
• Manage deviations, investigations, and corrective actions to ensure regulatory compliance
• Drive continuous improvement initiatives and support audits and inspections

Interested? For this role we're looking for the following education, experience and skills :

• Bachelor's or Master's degree in science, engineering, or related field
• Proven experience (10+ years) in biopharmaceutical manufacturing
• Experience in leading production teams in a regulated environment (including executive-level staff), high leadership skills
• Strong knowledge of Good Manufacturing Practices, industrial production processes and technologies, included upstream processes
• Strong communication, problem-solving, and decision-making skills
• Ability to work in highly dynamic environment and to handle challenging situations
• Fluent in French and English

#Biomanufacturing

About us

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9.000 people in all four corners of the globe, inspired by patients and driven by science.

Why work with us?

At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work. We 'go beyond' to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

At UCB, we've embraced a hybrid-first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.
Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us on [e-mail]. Please note should your enquiry not relate to adjustments; we will not be able to support you through this channel.