Head of Procurement Excellence

argenx US; Oost-Vlaanderen; On-site; EUR 120,000 - 180,000; Full time

Job summary

argenx is seeking a Head of Procurement Excellence to build and lead the Centre of Excellence powering our end-to-end procurement organization. You will drive procurement transformation, source-to-pay excellence, and digital/AI-enabled capabilities across the function to deliver measurable business value.

You will manage a global, multi-disciplinary team, partner with R&D, Quality, Regulatory, Finance, and Legal, and set a multi-year capability roadmap that positions procurement as a strategic

Qualifications

• Bachelor’s degree required; MBA or Master’s degree strongly preferred in Business, Supply Chain, Engineering, or related discipline.
• Significant experience leading procurement transformation, process excellence, or procurement Centres of Excellence within large global organizations.
• Experience leading digital and AI transformation initiatives within procurement.

Responsibilities

• Lead the global procurement transformation agenda across the end-to-end Source-to-Pay lifecycle.
• Define and execute a multi-year procurement capability roadmap with measurable impact.
• Build and develop advanced procurement capabilities, including analytics, supplier risk & performance management, and negotiation excellence.
• Partner with senior business leaders to align procurement priorities with broader enterprise objectives.

Skills

Procurement transformation

Process excellence

Centre of Excellence

AI transformation

Leadership

Cross-functional collaboration

Analytics

Supplier risk management

Negotiation excellence

Education

Bachelor's degree

MBA or Master’s degree

Job description

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.

We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients.

About the job

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases. We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients.

About The Role

As Head of Procurement Excellence, you will establish and lead the Centre of Excellence that powers Argenx's end-to-end procurement organization. You will be responsible for driving procurement transformation, advancing source-to-pay excellence, building next-generation capabilities, and accelerating the adoption of digital and AI-enabled solutions across the procurement landscape.

This is a highly strategic leadership role where you will define and execute a multi-year capability roadmap, embed new ways of working across the enterprise, and position procurement as a key value creator and growth enabler. You will lead a global, multidisciplinary team focused on delivering measurable business impact through innovation, operational excellence, and continuous improvement.

• Cross-Functional Collaboration
• Partner closely with R&D, Quality, Regulatory Affairs, Clinical Operations, Finance, Legal, and other functions to ensure sourcing strategies align with business priorities and development timelines.
• Enable seamless cross-functional ways of working that support efficiency, partnership, and procurement excellence.

Who You'll Work With

You will report to the Head of Procurement and serve as a member of the Procurement Leadership Team. You will collaborate closely with senior stakeholders across Finance, Digital Technology, Legal, Tech Ops, Research & Development functions while building/leading a global team spanning transformation, process excellence, analytics, AI, and advanced procurement capabilities.

What You'll Do

• Lead the global procurement transformation agenda, ensuring delivery of strategic initiatives and measurable business value.
• Drive continuous improvement and operational excellence across the end-to-end Source-to-Pay lifecycle.
• Define and execute the procurement AI and digital transformation roadmap, embedding innovative technologies into everyday decision-making.
• Build and lead agile procurement delivery teams focused on high-value projects, supplier optimization, and strategic business priorities.
• Establish and develop advanced procurement capabilities, including analytics, category management, supplier risk & performance management, and negotiation excellence.
• Create and govern procurement standards, policies, frameworks, and best practices across the enterprise.
• Partner with senior business leaders to align procurement priorities with broader enterprise objectives.
• Develop world-class procurement talent through capability building, coaching, training, and leadership development initiatives.
• Drive procurement performance through robust KPIs, executive dashboards, and continuous improvement programs.
• Champion innovation, collaboration, and a culture of value creation across the global procurement function.

Interested?

For this role we’re looking for:

• Bachelor’s degree required; MBA or Master’s degree strongly preferred in Business, Supply Chain, Engineering, or a related discipline.
• Significant experience leading procurement transformation, process excellence, or procurement Centres of Excellence within large global organizations.
• Experience leading digital and AI transformation initiatives within procuremen