Analytical Scientist - qPCR & ELISA

Pauwels Consulting; Geel; On-site; EUR 70,000 - 110,000; Full time

Job summary

Pauwels Consulting is supporting a leading biopharmaceutical client in Belgium seeking an expert to join their analytical science and technology team. The role focuses on driving analytical excellence for cell culture–based manufacturing by developing and validating critical methods.

You will lead method development, qualification, and transfer to manufacturing quality control, design DOE studies, and perform data trending and investigations of deviations, with strong documentation and writing

Qualifications

• PhD in Life Sciences, Biochemistry, Biotechnology, or equivalent.
• Proven experience in analytical method development, qualification, and validation in a cGMP environment.
• Hands-on qPCR and ELISA expertise, especially host cell impurity analysis.
• DOE experience for qualification of analytical assays and interpreting data.
• Analytical problem-solver with strong technical writing and multi-project management.
• Fluent English with good knowledge of Dutch.

Responsibilities

• Develop and validate analytical methods for cell culture-based processes.
• Execute method handovers from research to manufacturing science with documentation.
• Transfer validated methods to quality control and write protocols/reports.
• Design, develop, and validate analytical methods for existing and new processes.
• Independently design experiments and analytical studies.
• Perform data trending and monitoring of methods for long-term reliability.
• Conduct root cause investigations for analytical deviations and present findings.

Skills

qPCR

ELISA

DOE

Analytical method development

Qualification

Validation

cGMP

Data analysis

Technical writing

Project management

English

Dutch

Education

PhD in Life Sciences / Biochemistry / Biotechnology

Tools

qPCR apparatus

Job description

Our client, a leading biopharmaceutical organization, is seeking an expert to join their analytical science and technology department. The role focuses on driving analytical excellence by developing and implementing critical methods to ensure the quality and consistency of cell culture-based manufacturing processes.

• Act as a technical expert for analytical qPCR and ELISA methodologies.
• Execute method handovers from research to manufacturing science, ensuring comprehensive documentation and knowledge transfer.
• Coordinate the transfer of validated analytical methods to quality control, including troubleshooting and writing of protocols and reports.
• Design, develop, and validate analytical methods for both existing and new production processes.
• Independently design experiments and develop comprehensive analytical studies.
• Perform data trending and monitoring of analytical methods to ensure long‑term reliability and effectiveness.
• Conduct root cause investigations for analytical deviations and present findings to the technical team.

• You possess a PhD in Life Sciences, Biochemistry, Biotechnology, or equivalent through experience.
• You bring proven experience in analytical method development, qualification, and validation within a cGMP environment.
• You have strong hands‑on expertise with qPCR and ELISA, specifically for host cell impurity analysis.
• You have experience designing and executing DOE experiments for the qualification of analytical assays and interpreting complex datasets.
• You're an analytical problem‑solver with strong technical writing skills and the ability to manage multiple projects.
• You are fluent in English with a good knowledge of Dutch.

Nice to Haves

• Knowledge of protein characterization techniques such as SDS-PAGE or Western/Southern/Northern blots.
• Willingness to support both laboratory-based testing and desk-based analysis.