Translational Immunology Scientist – Immune Modulation

Novartis; Lavamünd; Vor Ort; EUR 70.000 - 129.000; Vollzeit

Benefits dieser Stelle

Insurance plans

Retirement plans

Wellbeing resources

Global recognition programs

Flexible & hybrid working

Zusammenfassung

Novartis in Basel, Switzerland, seeks a scientist for translational immunology in the Immunology Research Disease Area. You will lead mechanistic studies and biomarker development, using in vitro and in vivo models to advance immune-modulating therapies.

Requirements include MSc in Immunology or related field and at least 3 years of interdisciplinary research experience, with hands-on work in flow cytometry and molecular assays.

Qualifikationen

• MSc degree in Immunology, Biology, Molecular Medicine or a related field.
• At least 3 years of relevant research expertise in an interdisciplinary setting in academia or industry, bridging clinical and preclinical evidence
• Hands-on mastery of routine immunological/ cell biology/ molecular biology assays and in vitro human models relevant to autoinflammatory and systemic autoimmune diseases (such as primary cells, cell lines, flow cytometry, qPCR etc.)
• Experienced in collaboration with data scientists, ensuring high quality experimental design and reproducibility
• Proven track record of completing projects on schedule in view of narrow timelines
• Strong interest in working in a creative environment where you demonstrate proactiveness, a flexible attitude and scientific curiosity

Aufgaben

• Actively contribute to drug discovery and exploratory projects aiming at discovering new ways to modulate the immune system for the treatment of inflammatory and autoimmune diseases.
• Collaborate with quantitative scientists to design hypothesis-driven experiments and integrate experimental and biomarker data into models of autoimmune disease biology and therapeutic response.
• Design and conduct mechanistic experiments hands-on, utilizing human biosamples (such as blood/serum, PBMC, tissue biopsies) to generate translational data that inform project decisions, validate innovative concepts, elucidate mechanisms of action, and develop biomarker strategies.
• Plan and implement in vitro and ex vivo assays - including complex flow cytometry, cellular profiling, mechanistic cellular analyses, and examination of ex vivo samples derived from in vivo studies.
• Perform thorough analysis and interpretation of experimental results, critically evaluating whether hypotheses have been adequately tested, resolving any technical challenges, and determining subsequent experimental steps.
• Drive the development of novel hypotheses by integrating both internal and external scientific insights, proactively address research obstacles, and design strategic approaches to test these initial hypotheses.
• Work collaboratively as an integral part of cross-functional project teams, provide organized experiment record tracking and data analysis and be an active member of lab and project teams.
• Independently search for information in scientific and technical literature, establish new technologies in the lab and present your data within the team.
• Drive a culture of collaboration, talent development and integrity.

Kenntnisse

Immunology

MSc required

Flow cytometry

qPCR

Biomarker development

Project management

Data science collaboration

Cross-disciplinary teamwork

Ausbildung

MSc in Immunology or related field

Tools

qPCR

Flow cytometry

Jobbeschreibung

Novartis in Basel, Switzerland, seeks a scientist for translational immunology in the Immunology Research Disease Area. You will lead mechanistic studies and biomarker development, using in vitro and in vivo models to advance immune-modulating therapies.

Requirements include MSc in Immunology or related field and at least 3 years of interdisciplinary research experience, with hands-on work in flow cytometry and molecular assays.