CardioMetabolic Research Associate — In Vitro Development

F. Hoffmann-La Roche AG; Schweiz; Vor Ort; EUR 96.000 - 128.000; Vollzeit

Zusammenfassung

Roche is seeking an experienced Research Associate to advance cardiovascular and metabolic disease research in pRED. The role focuses on in vitro cellular models, primary cell culture, and molecular techniques to evaluate novel therapies.

You will design experiments, analyze data, and communicate findings while collaborating with multidisciplinary teams in Basel. The position requires a biology/biochemistry degree and 3+ years in pharma labs.

Qualifikationen

• Bachelor’s or Master’s degree in biology, biochemistry, or a related field.
• A minimum of 3 years in a pharma industry laboratory setting.
• Proficiency in cell culture, molecular biology, and biochemical techniques; familiarity with metabolic/cardiovascular cellular models.

Aufgaben

• Design and execute in‑vitro experiments using complex cellular models to evaluate the efficacy and safety of novel therapeutic candidates.
• Cultivate primary cell lines from human and animal tissues, optimizing protocols for primary cell isolation, differentiation and maintenance.
• Execute functional cell based and enzymatic assays to study metabolic pathways and other relevant readouts.
• Experience with advanced cellular and biochemical techniques, such as cell painting, and metabolic flux analysis using Seahorse to evaluate cellular bioenergetics.
• Strong knowledge of standard molecular biology techniques such as qPCR, Western Blot, Immunohistochemistry.
• Analyze experimental data with statistical tools, preparing high-quality reports and presentations to communicate findings effectively.
• Experience with animal handling, treatment and functional metabolic experimentation is advantageous.

Kenntnisse

Cell culture

Molecular biology

Biochemical techniques

qPCR

Western blot

Immunohistochemistry

Data analysis

Teamwork

English

Ausbildung

Bachelor’s or Master’s degree in biology/biochemistry or related field

Tools

Seahorse XF analyzer

Cell painting

Jobbeschreibung

Roche is seeking an experienced Research Associate to advance cardiovascular and metabolic disease research in pRED. The role focuses on in vitro cellular models, primary cell culture, and molecular techniques to evaluate novel therapies.

You will design experiments, analyze data, and communicate findings while collaborating with multidisciplinary teams in Basel. The position requires a biology/biochemistry degree and 3+ years in pharma labs.