Protein Coupling Scientist for Immunoassay Innovation

MADx – Macro Array Diagnostics GmbH; Wien; On-site; EUR 42,000 - 52,000; Full time

Benefits offered by this job

Public transport pass

Pluxee vouchers

Ownership from day one

Collaborative culture

Sustainability & inclusion

Job summary

MADx – Macro Array Diagnostics GmbH in Vienna seeks a Coupling Scientist to optimize protein coupling/conjugation methods for allergen and protein immobilization on microspheres used in immunoassays. You will improve efficiency, reproducibility, and stability while preparing processes for transfer to Engineering and Production.

Responsibilities include protocol standardization, documentation under GDP, and collaboration with cross-functional teams to ensure scalable, high-quality processes.

Qualifications

• BSc or MSc in chemistry, or equivalent.
• Experience with protein conjugation and immobilization.
• Good understanding of protein properties and coupling efficiency.
• Experience developing, optimizing, and troubleshooting lab methods and processes.
• Strong analytical and problem-solving skills with data-driven approach.
• GDP knowledge and accurate documentation practices.

Responsibilities

• Develop, evaluate, and optimize protein coupling and conjugation methods for immobilization of allergens, antibodies, and other proteins onto microspheres for immunoassay applications.
• Improve existing coupling methods for efficiency, reproducibility, stability, and overall assay performance.
• Troubleshoot coupling-related issues, identify root causes, and implement corrective actions and process improvements.
• Develop and standardize coupling protocols to ensure reliable results across proteins, batches, and production conditions.
• Prepare coupling methods and processes for transfer to Engineering and Production, including characterization and documentation.
• Collaborate with Engineering and Production to support method transfer, scale-up, and implementation of improved procedures.
• Document R&D activities and results in compliance with GDP and quality requirements; initiate changes as needed.
• Prepare and maintain department QM documentation, including coupling protocols, SOPs, and workflows.
• Initiate changes to methods and documentation to support continuous improvement and quality compliance.

Skills

Protein chemistry

Conjugation techniques

Process optimization

Troubleshooting

Documentation & GDP

Interdisciplinary collaboration

Data-driven decisions

English communication

Education

BSc or MSc in chemistry

Job description

MADx – Macro Array Diagnostics GmbH in Vienna seeks a Coupling Scientist to optimize protein coupling/conjugation methods for allergen and protein immobilization on microspheres used in immunoassays. You will improve efficiency, reproducibility, and stability while preparing processes for transfer to Engineering and Production.

Responsibilities include protocol standardization, documentation under GDP, and collaboration with cross-functional teams to ensure scalable, high-quality processes.