Organoid & iPSC Scientist for Human-First Drug Discovery

Parallel Bio; Wien; Vor Ort; EUR 36.000 - 44.000; Vollzeit

Zusammenfassung

Parallel Bio in Vienna seeks a driven scientist to advance human organoid models and immune organoid development. You will derive iPSC lines, perform quality control, and work to improve culture longevity and assay readouts including flow cytometry, qPCR, ELISA, and imaging.

You will also prepare samples for sequencing, document procedures, and train colleagues in a collaborative, fast-paced environment. Weekend work rotation applies with competitive compensation.

Qualifikationen

• MSc in molecular biology, cell biology, immunology, bioengineering or related field.
• Hands-on aseptic human pluripotent stem cell culture experience (iPSC/ESC) preferred.
• Experience with standard molecular and cellular assays: flow cytometry, qPCR, ELISA.
• Experience with reprogramming, clonal derivation, karyotyping or genotyping, or cryopreservation at scale is an advantage.
• 3D culture, organoid or spheroid experience; immunology knowledge a plus.
• Experience preparing samples for NGS is welcome.

Aufgaben

• Derive iPSC lines from donor blood and manage colony picking, expansion, and cryopreservation.
• Interpret cell line quality control data and determine passed/failed samples per acceptance criteria.
• Understand sources of variation affecting iPSC-generation and biobank quality.
• Differentiate iPSCs toward immune organoids using in-house protocols.
• Maintain iPSC and primary cultures to a consistent standard and optimise longevity and function.
• Run readouts of organoid functionality: flow cytometry panels, qPCR, ELISA, imaging.
• Prepare samples for external sequencing and manage submissions.
• Document in ELN and write Work Instructions and SOPs.

Kenntnisse

English proficiency

Teamwork

Attention to detail

Documentation

Cross-disciplinary collaboration

Ausbildung

MSc in molecular biology or related field

Tools

Flow cytometry

qPCR

ELISA

Karyotyping/genotyping

Cryopreservation

NGS sample prep

Jobbeschreibung

Parallel Bio in Vienna seeks a driven scientist to advance human organoid models and immune organoid development. You will derive iPSC lines, perform quality control, and work to improve culture longevity and assay readouts including flow cytometry, qPCR, ELISA, and imaging.

You will also prepare samples for sequencing, document procedures, and train colleagues in a collaborative, fast-paced environment. Weekend work rotation applies with competitive compensation.