Chemical Engineer - Pharmaceutical Intermediates Production

Placements24; Lorenziberg; Presencial; EUR 48 000 - 64 000; Tempo integral

Resumo da oferta

Placements24 is seeking a skilled Chemical Engineer to oversee and optimize production of pharmaceutical intermediates at an on-site facility in Queenstown, Eastern Cape. You will ensure quality, safety, and efficiency of organic synthesis processes in a GMP-regulated environment.

Responsibilities include process monitoring, optimization, SOP development, and collaboration with QA, QC, and R&D to drive continuous improvement and cost reduction.

Qualificações

• Bachelor's degree in Chemical Engineering.
• Minimum of 6 years of experience in chemical engineering with focus on pharmaceutical intermediates or API manufacturing.
• Strong knowledge of organic chemistry and reaction engineering relevant to pharmaceutical synthesis.
• Proven experience in a cGMP-compliant environment.
• Familiarity with process validation, scale-up, and technology.

Responsabilidades

• Manage and optimize chemical synthesis processes for pharmaceutical intermediates.
• Ensure production processes comply with cGMP guidelines and regulatory requirements.
• Monitor process performance, identify deviations, and implement corrective actions.
• Conduct process validation activities and prepare validation reports.
• Develop and implement Standard Operating Procedures (SOPs) for all production activities.
• Troubleshoot equipment and process-related issues to minimize downtime and maintain product quality.
• Collaborate with Quality Assurance, Quality Control, and R&D departments.
• Lead or participate in Process Hazard Analyses (PHAs) and risk assessments.
• Identify and implement opportunities for process improvement, cost reduction, and yield enhancement.
• Train operations personnel on new processes and equipment.
• Manage raw material inventory and ensure timely procurement for production needs.
• Maintain accurate production records and batch documentation.

Formação académica

Bachelor's degree in Chemical Engineering

Descrição da oferta de emprego

About the Role

Our client, a reputable pharmaceutical manufacturer, is seeking a skilled Chemical Engineer to oversee and optimize the production of critical pharmaceutical intermediates at their facility in Queenstown, Eastern Cape. This role is essential for ensuring the consistent quality, safety, and efficiency of chemical synthesis processes that form the building blocks of vital medications. The successful candidate will be responsible for process monitoring, troubleshooting, continuous improvement initiatives, and ensuring strict adherence to Good Manufacturing Practices (GMP). This is an on-site position requiring a strong understanding of organic synthesis, chemical engineering principles, and the pharmaceutical regulatory landscape.

Key Responsibilities

• Manage and optimize chemical synthesis processes for pharmaceutical intermediates.
• Ensure production processes comply with cGMP guidelines and regulatory requirements.
• Monitor process performance, identify deviations, and implement corrective actions.
• Conduct process validation activities and prepare validation reports.
• Develop and implement Standard Operating Procedures (SOPs) for all production activities.
• Troubleshoot equipment and process-related issues to minimize downtime and maintain product quality.
• Collaborate with Quality Assurance, Quality Control, and R&D departments.
• Lead or participate in Process Hazard Analyses (PHAs) and risk assessments.
• Identify and implement opportunities for process improvement, cost reduction, and yield enhancement.
• Train operations personnel on new processes and equipment.
• Manage raw material inventory and ensure timely procurement for production needs.
• Maintain accurate production records and batch documentation.

Requirements

• Bachelor's degree in Chemical Engineering.
• Minimum of 6 years of experience in chemical engineering, with a significant focus on pharmaceutical intermediate or API manufacturing.
• Strong knowledge of organic chemistry and reaction engineering relevant to pharmaceutical synthesis.
• Proven experience working in a cGMP-compliant environment.
• Familiarity with process validation, scale-up, and technology