Senior Chemical Engineer - Pharma Intermediates & GMP

Placements24; Lorenziberg; On-site; EUR 48,000 - 64,000; Full time

Job summary

Placements24 is seeking a skilled Chemical Engineer to oversee and optimize production of pharmaceutical intermediates at an on-site facility in Queenstown, Eastern Cape. You will ensure quality, safety, and efficiency of organic synthesis processes in a GMP-regulated environment.

Responsibilities include process monitoring, optimization, SOP development, and collaboration with QA, QC, and R&D to drive continuous improvement and cost reduction.

Qualifications

• Bachelor's degree in Chemical Engineering.
• Minimum of 6 years of experience in chemical engineering with focus on pharmaceutical intermediates or API manufacturing.
• Strong knowledge of organic chemistry and reaction engineering relevant to pharmaceutical synthesis.
• Proven experience in a cGMP-compliant environment.
• Familiarity with process validation, scale-up, and technology.

Responsibilities

• Manage and optimize chemical synthesis processes for pharmaceutical intermediates.
• Ensure production processes comply with cGMP guidelines and regulatory requirements.
• Monitor process performance, identify deviations, and implement corrective actions.
• Conduct process validation activities and prepare validation reports.
• Develop and implement Standard Operating Procedures (SOPs) for all production activities.
• Troubleshoot equipment and process-related issues to minimize downtime and maintain product quality.
• Collaborate with Quality Assurance, Quality Control, and R&D departments.
• Lead or participate in Process Hazard Analyses (PHAs) and risk assessments.
• Identify and implement opportunities for process improvement, cost reduction, and yield enhancement.
• Train operations personnel on new processes and equipment.
• Manage raw material inventory and ensure timely procurement for production needs.
• Maintain accurate production records and batch documentation.

Education

Bachelor's degree in Chemical Engineering

Job description

Placements24 is seeking a skilled Chemical Engineer to oversee and optimize production of pharmaceutical intermediates at an on-site facility in Queenstown, Eastern Cape. You will ensure quality, safety, and efficiency of organic synthesis processes in a GMP-regulated environment.

Responsibilities include process monitoring, optimization, SOP development, and collaboration with QA, QC, and R&D to drive continuous improvement and cost reduction.