Senior Research Scientist - Pharmacology

Placements24; Klerksdorp; Hybrid; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Hybrid work environment

Health insurance

Retirement plan

Access to cutting-edge facilities

Job summary

Placements24 in Klerksdorp, South Africa, seeks a Senior Research Scientist in Pharmacology to lead preclinical studies and contribute to the drug discovery pipeline. You will design and execute in vivo and in vitro experiments, and analyze PK/PD data in a fast-paced, collaborative environment.

The ideal candidate holds a PhD in Pharmacology or Toxicology with at least 7 years of industry experience, and demonstrates strong scientific writing and presentation skills.

Qualifications

• PhD in Pharmacology, Toxicology, or a related life science discipline is required.
• Minimum 7 years of relevant research experience in pharma/biotech.
• Proven expertise in designing and executing preclinical pharmacological studies.

Responsibilities

• Design and conduct pharmacological studies to evaluate efficacy and safety of drug candidates.
• Develop and validate in vitro and in vivo assay systems for disease areas.
• Analyze pharmacological data, interpret results, and generate study reports.
• Contribute to selection and prioritization of drug candidates for development.
• Collaborate with medicinal chemists, toxicologists and R&D team members.

Skills

PK/PD principles

Preclinical pharmacology

In vivo studies

In vitro studies

Scientific communication

Education

PhD in Pharmacology or Toxicology

Job description

About the Role

Our client is seeking an accomplished Senior Research Scientist with a strong background in Pharmacology to join their R&D team in Klerksdorp . This role is central to discovering and developing novel therapeutic agents. You will be responsible for designing and executing in vivo and in vitro pharmacological studies, analyzing drug efficacy and safety profiles, and contributing significantly to the drug discovery pipeline. The ideal candidate will possess a deep understanding of drug action mechanisms, a proven track record in preclinical research, and a commitment to scientific excellence within a fast-paced, collaborative research environment.

Key Responsibilities

• Design and conduct pharmacological studies to evaluate the efficacy and safety of potential drug candidates.
• Develop and validate in vitro and in vivo assay systems relevant to specific disease areas.
• Analyze pharmacological data, interpret results, and generate comprehensive study reports.
• Contribute to the selection and prioritization of drug candidates for further development.
• Collaborate with medicinal chemists, toxicologists, and other R&D team members.
• Stay current with scientific literature and emerging trends in pharmacology and drug development.

Requirements

• Ph.D. in Pharmacology, Toxicology, or a related life science discipline.
• Minimum of 7 years of relevant research experience in the pharmaceutical or biotechnology industry.
• Proven expertise in designing and executing preclinical pharmacological studies.
• Strong understanding of pharmacokinetic (PK) and pharmacodynamic (PD) principles.
• Experience with various animal models and standard laboratory techniques.
• Excellent scientific writing, presentation, and communication skills.

Benefits

• Competitive salary and bonus program.
• Comprehensive health, dental, and vision insurance.
• Generous retirement savings plan.
• Hybrid work environment offering flexibility.
• Access to cutting-edge research facilities and equipment in Klerksdorp .