Senior Process Development Scientist

Placements24; Rustenburg; Híbrido; ZAR 1 200 000 - 1 800 000; Tempo integral

Vantagens oferecidas por esta oferta de emprego

Annual performance bonus

Retirement annuity

Private medical aid

Training budgets for conferences/works

Generous annual leave

Flexible working arrangements

Modern laboratory facilities

Resumo da oferta

Placements24 is recruiting a Senior Process Development Scientist for our client in Rustenburg, North West, South Africa. You will design, optimize, and scale biopharmaceutical manufacturing processes, turning lab discoveries into robust production methods with GMP-compliant workflows.

The role requires a PhD/MSc in Biochemical Engineering or related field, 5+ years in biopharma development, and hands-on experience in upstream or downstream processing, DoE, and data analysis.

Qualificações

• Master's or PhD in Biochemical Engineering, Chemical Engineering, Biotechnology, or a related life science field.
• Minimum 5 years of progressive experience in biopharmaceutical process development and scale-up.
• Demonstrated expertise in upstream or downstream processing.
• Proven experience with Design of Experiments (DoE) and statistical analysis tools.
• Familiarity with GMP regulations and guidelines relevant to biopharmaceutical manufacturing.
• Strong analytical and problem-solving skills, with the ability to work effectively under pressure.
• Excellent written and verbal communication skills, including technical report writing and presentation abilities.
• Experience working in a Rustenburg, North West-based research or manufacturing environment is beneficial.

Responsabilidades

• Design and execute experiments to optimize biopharmaceutical manufacturing processes, including cell culture, fermentation, purification, and formulation.
• Develop and validate scalable processes that meet regulatory requirements (e.g., GMP) and product specifications.
• Perform risk assessments and implement control strategies to ensure process robustness and product consistency.
• Utilize Design of Experiments (DoE) principles to efficiently optimize process parameters.
• Troubleshoot and resolve complex process-related issues, ensuring minimal disruption to production timelines.
• Analyze process data, interpret results, and generate detailed technical reports and development protocols.
• Lead technology transfer activities for new processes from development to manufacturing scale.
• Collaborate with cross-functional teams, including manufacturing, quality assurance, and regulatory affairs.
• Mentor and provide technical guidance to junior scientists and engineers within the process development group.
• Stay current with industry trends, new technologies, and regulatory guidelines relevant to biopharmaceutical process development.

Conhecimentos

DoE

GMP familiarity

Bioprocessing

Statistical analysis

Formação académica

Master's or PhD in Biochemical Engineering

Ferramentas

Bioreactor operation

Chromatography

Filtration

Viral inactivation

Descrição da oferta de emprego

About the Role

Our client, a dynamic biotechnology firm, is actively seeking a highly experienced Senior Process Development Scientist to join their innovative team based in **Rustenburg, North West**. This critical role will focus on the design, optimization, and scale-up of biopharmaceutical manufacturing processes. You will be instrumental in translating laboratory-scale discoveries into robust, commercially viable production methods, ensuring product quality and efficiency. The ideal candidate possesses a deep understanding of upstream or downstream bioprocessing, coupled with a strong scientific foundation and hands‑on experience in process development. This is a unique opportunity to contribute to the development of life‑saving therapies within a rapidly growing sector. We are committed to fostering a collaborative research environment that encourages innovation and scientific excellence. The position comes with an attractive salary and a comprehensive benefits package, reflecting the significance of this role in our **Rustenburg, North West** operations.

Key Responsibilities

• Design and execute experiments to optimize biopharmaceutical manufacturing processes, including cell culture, fermentation, purification, and formulation.
• Develop and validate scalable processes that meet regulatory requirements (e.g., GMP) and product specifications.
• Perform risk assessments and implement control strategies to ensure process robustness and product consistency.
• Utilize Design of Experiments (DoE) principles to efficiently optimize process parameters.
• Troubleshoot and resolve complex process-related issues, ensuring minimal disruption to production timelines.
• Analyze process data, interpret results, and generate detailed technical reports and development protocols.
• Lead technology transfer activities for new processes from development to manufacturing scale.
• Collaborate with cross-functional teams, including manufacturing, quality assurance, and regulatory affairs.
• Mentor and provide technical guidance to junior scientists and engineers within the process development group.
• Stay current with industry trends, new technologies, and regulatory guidelines relevant to biopharmaceutical process development.

Requirements

• A Master's or Ph.D. in Biochemical Engineering, Chemical Engineering, Biotechnology, or a related life science field.
• A minimum of 5 years of progressive experience in biopharmaceutical process development and scale-up.
• Demonstrated expertise in upstream (e.g., bioreactor operation, cell culture optimization) or downstream (e.g., chromatography, filtration, viral inactivation) processing.
• Proven experience with Design of Experiments (DoE) and statistical analysis tools.
• Familiarity with GMP regulations and guidelines relevant to biopharmaceutical manufacturing.
• Strong analytical and problem-solving skills, with the ability to work effectively under pressure.
• Excellent written and verbal communication skills, including technical report writing and presentation abilities.
• Experience working in a **Rustenburg, North West**-based research or manufacturing environment is beneficial.

Benefits

• Our client offers a competitive base salary complemented by annual performance bonuses.
• A robust retirement annuity scheme and comprehensive private medical aid coverage are provided.
• We invest in our employees' growth through dedicated training budgets for conferences, workshops, and professional certifications.
• Employees receive an attractive annual leave allowance, generous sick leave provisions, and observance of all national public holidays.
• Support for work-life balance is a priority, with flexible working arrangements where applicable.
• The **Rustenburg, North West** site features modern laboratory facilities and a collaborative team atmosphere.