Biopharmaceutical Process Development Scientist

Placements24; Soweto; Presencial; ZAR 900.000 - 1.300.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Comprehensive health, dental, and view

Performance-based bonus and annuals

Generous paid time off and holidays

Professional development opportunities

Retirement savings plan with employer

Access to state-of-the-art bioprocess野

Dynamic and collaborative work culture

Career advancement prospects

Descripción de la vacante

Placements24 in Soweto, Gauteng, seeks a Biopharmaceutical Process Development Scientist to lead upstream and downstream development of biologics. You will design DoE experiments, develop analytical methods, ensure cGMP compliance, and drive technology transfer to manufacturing teams.

This role offers exposure to cutting-edge bioprocessing and collaboration across functions in a dynamic environment. You will stay current with industry advances and contribute to a strong scientific culture in

Formación

• Ph.D. or Master's in Chemical Engineering, Biochemical Engineering, Biotechnology, or related field.
• Minimum 4 years of hands-on biopharmaceutical process development experience (upstream and downstream).
• Experience with cell culture/fermentation and/or protein purification techniques.
• Proficiency in process characterization, scale-up, and technology transfer.
• Experience with PAT and DoE is highly desirable.
• Strong analytical and problem-solving abilities with data interpretation.
• Excellent written and verbal communication; technical report writing.
• Ability to work independently and in cross-functional teams.
• Knowledge of regulatory requirements (FDA/EMA) is a plus.
• Commitment to scientific excellence in the Soweto region.

Responsabilidades

• Lead and execute upstream (cell culture) and downstream (purification) process development.
• Optimize biomanufacturing processes to improve yield and purity while reducing costs.
• Develop and validate analytical methods for in-process controls and product characterization.
• Design and run DoE-based experiments for process understanding and optimization.
• Troubleshoot technical challenges during development and scale-up.
• Prepare process development reports, tech transfer documents, and regulatory filings.
• Collaborate with manufacturing teams to ensure successful tech transfer.
• Stay updated on bioprocessing advancements and ensure cGMP compliance.
• Contribute to a strong scientific culture within the group.

Conocimientos

Cell culture

Upstream processing

Downstream purification

Process characterization

DoE (Design of Experiments)

PAT (Process Analytical Technology)

Analytical skills

Regulatory knowledge (FDA/EMA)

Communication skills

Team collaboration

Educación

PhD or Master's in Chemical Engineering, Biochemical Engineering, Biotechnology

Herramientas

Tech transfer

Descripción del empleo

About the Role

Our client, a leading biopharmaceutical company dedicated to advancing novel therapeutics, is seeking a talented Biopharmaceutical Process Development Scientist to join their innovative team in Soweto, Gauteng . This role focuses on the development, optimization, and scale-up of manufacturing processes for biologics, including monoclonal antibodies and recombinant proteins. The ideal candidate will possess a strong understanding of cell culture, upstream processing, downstream purification, and process characterization techniques. You will be instrumental in ensuring the efficient and robust production of high-quality biopharmaceuticals, contributing significantly to bringing life-changing treatments to patients. This is an exciting opportunity for a scientist passionate about bioprocess engineering to grow their career within a rapidly evolving sector in Soweto .

Key Responsibilities

• Lead and execute process development activities for upstream (cell culture) and downstream (purification) operations of biologics.
• Optimize existing biomanufacturing processes to improve yield, purity, and reduce costs.
• Develop and validate robust analytical methods for in-process controls and product characterization.
• Design and conduct experiments using Design of Experiments (DoE) principles for process understanding and optimization.
• Troubleshoot and resolve technical challenges encountered during process development and scale-up activities.
• Prepare comprehensive process development reports, technology transfer documents, and contributions to regulatory filings.
• Collaborate with upstream and downstream manufacturing teams to ensure successful technology transfer and implementation of processes.
• Stay current with the latest advancements in bioprocessing technologies and methodologies.
• Ensure all activities are conducted in compliance with cGMP, safety, and environmental regulations.
• Contribute to building a strong scientific and technical culture within the biopharmaceutical development group in Gauteng .

Requirements

• Ph.D. or Master's degree in Chemical Engineering, Biochemical Engineering, Biotechnology, or a related field.
• Minimum of 4 years of hands‑on experience in biopharmaceutical process development, including upstream and downstream processing.
• Demonstrated experience with cell culture/fermentation and/or protein purification techniques.
• Proficiency with process characterization, scale‑up, and technology transfer principles.
• Experience with process analytical technology (PAT) and DoE is highly desirable.
• Strong analytical and problem‑solving skills, with the ability to interpret complex data.
• Excellent written and verbal communication skills, with experience in technical report writing.
• Ability to work independently and as part of a cross‑functional team.
• Knowledge of regulatory requirements for biopharmaceuticals (e.g., FDA, EMA) is a plus.
• Commitment to scientific excellence and innovation in the Soweto region.

Benefits

• Annual salary of R.
• Comprehensive health, dental, and vision insurance coverage.
• Performance‑based bonus and annual reviews.
• Generous paid time off and company holidays.
• Opportunities for professional development, including attending conferences and workshops.
• Retirement savings plan with employer matching.
• Access to state‑of‑the‑art bioprocessing equipment and facilities.
• A dynamic and collaborative work environment focused on innovation in Gauteng .
• Career advancement prospects within a leading biopharmaceutical company.