Senior Pharmacologist: PK/PD & In Vivo Expert

Placements24; Upington; Hybrid; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Competitive salary and bonus

Comprehensive health, dental, and eye

Retirement savings plan with company 1

Generous paid time off and holidays

Professional development opportunities

Access to cutting-edge facilities

Supportive and collaborative work env

Job summary

Placements24 client, a leading biopharmaceutical company, seeks a Senior Pharmacologist to join their R&D team in Upington, Northern Cape. The role involves designing and executing in vivo and in vitro studies to assess efficacy, safety and PK/PD profiles of novel drug candidates.

You will mentor junior researchers, collaborate with chemists and toxicologists, prepare regulatory documents, stay current with pharmacology advances, and ensure GLP compliance in a cutting-edge research facility.

Qualifications

• Ph.D. in Pharmacology, Toxicology, Physiology, or a related life science discipline.
• Minimum of 6 years of experience in drug discovery and development, preferably within the pharmaceutical or biotechnology industry.
• Proven experience in designing and executing in vivo efficacy and safety studies.
• Strong understanding of PK/PD principles and analysis.
• Experience with various assay technologies (e.g., ELISA, flow cytometry, cell-based assays).
• Familiarity with regulatory requirements for drug development (e.g., FDA, EMA).
• Excellent scientific writing and presentation skills.
• Strong analytical and problem-solving abilities.
• Ability to work independently and lead research projects.

Responsibilities

• Design, conduct, and interpret complex in vivo and in vitro pharmacological studies.
• Develop and validate assays to assess drug efficacy, safety, and mechanism of action.
• Analyze pharmacokinetic (PK) and pharmacodynamic (PD) data.
• Prepare high-quality study reports, protocols, and regulatory documents.
• Collaborate closely with medicinal chemists, toxicologists, and other R&D scientists.
• Present research findings at internal meetings and external scientific conferences.
• Stay current with advancements in pharmacology, drug discovery, and relevant therapeutic areas.
• Ensure compliance with GLP and other relevant regulatory standards.
• Mentor junior researchers and contribute to the overall scientific direction of the department.

Skills

Pharmacology expertise

PK/PD analysis

Regulatory knowledge

Scientific writing

Leadership

Data analysis

Education

PhD in Pharmacology

Tools

ELISA

Flow cytometry

Cell-based assays

Job description

Placements24 client, a leading biopharmaceutical company, seeks a Senior Pharmacologist to join their R&D team in Upington, Northern Cape. The role involves designing and executing in vivo and in vitro studies to assess efficacy, safety and PK/PD profiles of novel drug candidates.

You will mentor junior researchers, collaborate with chemists and toxicologists, prepare regulatory documents, stay current with pharmacology advances, and ensure GLP compliance in a cutting-edge research facility.