Paarl-Based Lead Pharmacologist, Preclinical Research

Placements24; Paarl; On-site; ZAR 1,200,000 - 2,000,000; Full time

Benefits offered by this job

Bonuses

Health insurance

Retirement plan

Paid time off

Conference funding

Job summary

Placements24 is seeking a Lead Pharmacologist to drive preclinical research at our Paarl facility. You will design and oversee in vivo and in vitro studies, interpret PK/PD data, and guide a team of pharmacologists and technicians.

The ideal candidate holds a PhD in Pharmacology or Toxicology, with 7+ years in drug discovery. You will collaborate across disciplines, ensure GLP compliance, and contribute to regulatory filings and strategic decisions.

Qualifications

• Ph.D. in Pharmacology, Toxicology, or related life science.
• ≥7 years post‑doctoral or industry experience in drug discovery and development.
• Proven expertise in in vivo efficacy models and PK studies.
• Strong knowledge of DMPK principles.
• Experience leading a research team.
• Excellent written and verbal communication; publications.

Responsibilities

• Design and oversee in vivo and in vitro pharmacological studies.
• Analyze efficacy, toxicity, and PK/PD data.
• Develop and validate preclinical assays and models.
• Mentor and direct a research team.
• Collaborate with medicinal chemistry, toxicology, and clinical teams.
• Prepare study reports and contribute to regulatory filings.
• Present findings at meetings and conferences.
• Ensure GLP and animal welfare compliance in Paarl.

Skills

Leadership

Data analysis

Communication

Team mentorship

Education

PhD in Pharmacology or related field

Tools

Data analysis software

Scientific databases

Job description

Placements24 is seeking a Lead Pharmacologist to drive preclinical research at our Paarl facility. You will design and oversee in vivo and in vitro studies, interpret PK/PD data, and guide a team of pharmacologists and technicians.

The ideal candidate holds a PhD in Pharmacology or Toxicology, with 7+ years in drug discovery. You will collaborate across disciplines, ensure GLP compliance, and contribute to regulatory filings and strategic decisions.