Senior Pharmacologist

Placements24; Upington; Hybrid; ZAR 1,200,000 - 1,800,000; Full time

Benefits offered by this job

Competitive salary and bonus

Comprehensive health, dental, and eye

Retirement savings plan with company 1

Generous paid time off and holidays

Professional development opportunities

Access to cutting-edge facilities

Supportive and collaborative work env

Job summary

Placements24 client, a leading biopharmaceutical company, seeks a Senior Pharmacologist to join their R&D team in Upington, Northern Cape. The role involves designing and executing in vivo and in vitro studies to assess efficacy, safety and PK/PD profiles of novel drug candidates.

You will mentor junior researchers, collaborate with chemists and toxicologists, prepare regulatory documents, stay current with pharmacology advances, and ensure GLP compliance in a cutting-edge research facility.

Qualifications

• Ph.D. in Pharmacology, Toxicology, Physiology, or a related life science discipline.
• Minimum of 6 years of experience in drug discovery and development, preferably within the pharmaceutical or biotechnology industry.
• Proven experience in designing and executing in vivo efficacy and safety studies.
• Strong understanding of PK/PD principles and analysis.
• Experience with various assay technologies (e.g., ELISA, flow cytometry, cell-based assays).
• Familiarity with regulatory requirements for drug development (e.g., FDA, EMA).
• Excellent scientific writing and presentation skills.
• Strong analytical and problem-solving abilities.
• Ability to work independently and lead research projects.

Responsibilities

• Design, conduct, and interpret complex in vivo and in vitro pharmacological studies.
• Develop and validate assays to assess drug efficacy, safety, and mechanism of action.
• Analyze pharmacokinetic (PK) and pharmacodynamic (PD) data.
• Prepare high-quality study reports, protocols, and regulatory documents.
• Collaborate closely with medicinal chemists, toxicologists, and other R&D scientists.
• Present research findings at internal meetings and external scientific conferences.
• Stay current with advancements in pharmacology, drug discovery, and relevant therapeutic areas.
• Ensure compliance with GLP and other relevant regulatory standards.
• Mentor junior researchers and contribute to the overall scientific direction of the department.

Skills

Pharmacology expertise

PK/PD analysis

Regulatory knowledge

Scientific writing

Leadership

Data analysis

Education

PhD in Pharmacology

Tools

ELISA

Flow cytometry

Cell-based assays

Job description

About the Role

Our client, a leading biopharmaceutical company, is actively seeking a Senior Pharmacologist to join their esteemed research and development department in Upington, Northern Cape . This critical role will involve designing and executing in vivo and in vitro studies to assess the efficacy, safety, and pharmacokinetic profiles of novel drug candidates. You will be instrumental in advancing our client's pipeline towards clinical development, working collaboratively within multidisciplinary teams. The ideal candidate will possess a deep understanding of drug action mechanisms, experience with regulatory guidelines, and a passion for translating scientific discoveries into potential therapies. This position offers a unique opportunity to contribute significantly to drug development in a supportive and advanced research setting. The role is based at our client's research facility in Upington, Northern Cape .

Key Responsibilities

• Design, conduct, and interpret complex in vivo and in vitro pharmacological studies.
• Develop and validate assays to assess drug efficacy, safety, and mechanism of action.
• Analyze pharmacokinetic (PK) and pharmacodynamic (PD) data.
• Prepare high-quality study reports, protocols, and regulatory documents.
• Collaborate closely with medicinal chemists, toxicologists, and other R&D scientists.
• Present research findings at internal meetings and external scientific conferences.
• Stay current with advancements in pharmacology, drug discovery, and relevant therapeutic areas.
• Ensure compliance with GLP and other relevant regulatory standards.
• Mentor junior researchers and contribute to the overall scientific direction of the department.

Requirements

• Ph.D. in Pharmacology, Toxicology, Physiology, or a related life science discipline.
• Minimum of 6 years of experience in drug discovery and development, preferably within the pharmaceutical or biotechnology industry.
• Proven experience in designing and executing in vivo efficacy and safety studies.
• Strong understanding of PK/PD principles and analysis.
• Experience with various assay technologies (e.g., ELISA, flow cytometry, cell-based assays).
• Familiarity with regulatory requirements for drug development (e.g., FDA, EMA).
• Excellent scientific writing and presentation skills.
• Strong analytical and problem-solving abilities.
• Ability to work independently and lead research projects.

Benefits

• Competitive salary and bonus opportunities.
• Comprehensive health, dental, and vision insurance.
• Retirement savings plan with company match.
• Generous paid time off and holidays.
• Opportunities for professional development and continuing education.
• Access to cutting-edge research facilities and technologies.
• Supportive and collaborative work environment.