Senior Computational Scientist — Drug Discovery Leader

Placements24; Benoni; Sur place; ZAR 1 100 000 - 1 500 000; Plein temps

Avantages offerts par ce poste

Competitive salary & bonuses

Health insurance

Training & conference funding

Generous annual leave & wellness

Résumé du poste

Placements24 is seeking a Senior Computational Scientist to join a leading biopharmaceutical drug discovery team in Benoni, Gauteng. You will apply advanced computational methods to biological and chemical data, collaborating with chemists, biologists and pharmacologists to design experiments and build predictive models.

The ideal candidate holds a PhD in computational chemistry or cheminformatics, 5+ years in drug discovery, and strong expertise in modeling, docking and QSAR, with Python and

Qualifications

• PhD in Computational Chemistry, Cheminformatics or related field.
• Minimum 5 years in computational drug discovery in pharma/biotech.
• Strong modeling, docking, and QSAR expertise.

Responsabilités

• Develop and apply computational methods for molecular modeling and structure-based drug design.
• Utilize cheminformatics tools and databases to analyze chemical libraries and identify leads.
• Build predictive models for ADMET, efficacy, and target engagement.
• Collaborate with medicinal chemists to guide compound design and optimization.
• Analyze large datasets from HTS, omics, and in vivo studies.
• Develop data analysis workflows and pipelines for drug discovery projects.
• Communicate complex computational findings to cross-functional teams.
• Stay updated on emerging computational techniques in drug discovery.
• Contribute to IP development through patent filings.
• Manage projects and ensure timely computational support.

Connaissances

Python scripting

Data analysis

Machine learning

Communication skills

Formation

PhD in Computational Chemistry / Cheminformatics / Pharmaceutical Sciences

Outils

Schrodinger

MOE

OpenEye

Description du poste

Placements24 is seeking a Senior Computational Scientist to join a leading biopharmaceutical drug discovery team in Benoni, Gauteng. You will apply advanced computational methods to biological and chemical data, collaborating with chemists, biologists and pharmacologists to design experiments and build predictive models.

The ideal candidate holds a PhD in computational chemistry or cheminformatics, 5+ years in drug discovery, and strong expertise in modeling, docking and QSAR, with Python and