Senior Cheminformatics Scientist - Drug Discovery (Hybrid)

Placements24; Randburg; Hybrid; ZAR 900,000 - 1,350,000; Full time

Benefits offered by this job

Highly competitive salary and bonus

Comprehensive health, dental, and life

Retirement savings plan

Hybrid work environment and training

Access to cutting-edge computational资源

Job summary

Placements24 is seeking an experienced Senior Computational Scientist in Randburg for a hybrid role focused on cheminformatics in drug discovery. You will develop computational models, manage chemical datasets, and collaborate with chemists and biologists to accelerate candidate design.

The role requires a PhD in a related field and at least 5 years of experience with Python, RDKit/Open Babel, and molecular modeling tools.

Qualifications

• PhD in Cheminformatics or related field.
• Minimum 5 years in computational chemistry or cheminformatics in pharma/biotech.
• Proficiency in Python and RDKit/Open Babel.
• Experience with molecular modeling and QSAR workflows.

Responsibilities

• Develop and apply computational chemistry and cheminformatics techniques to support drug discovery programs.
• Design, build, and maintain databases of chemical compounds and properties.
• Implement QSAR models and other predictive computational models.
• Utilize molecular modeling and simulation techniques to analyze molecular interactions and properties.
• Collaborate with medicinal chemists to design new molecules with desired properties.
• Analyze large chemical datasets to identify trends, patterns, and potential leads.
• Develop and optimize workflows for virtual screening and library design.
• Communicate computational findings to cross-functional teams.
• Stay abreast of developments in cheminformatics and drug discovery.

Skills

Python programming

QSAR & ML techniques

Molecular modeling & docking

Data analysis & statistics

Cross-functional communication

Education

PhD in Cheminformatics or related field

Tools

RDKit

Open Babel

Molecular docking software

Molecular dynamics software

Job description

Placements24 is seeking an experienced Senior Computational Scientist in Randburg for a hybrid role focused on cheminformatics in drug discovery. You will develop computational models, manage chemical datasets, and collaborate with chemists and biologists to accelerate candidate design.

The role requires a PhD in a related field and at least 5 years of experience with Python, RDKit/Open Babel, and molecular modeling tools.