Senior Bioprocess Engineer

Placements24; Vereeniging; On-site; ZAR 1,100,000 - 1,900,000; Full time

Benefits offered by this job

Highly competitive salary

Performance-based bonus

Medical, dental, and vision insurance

Retirement savings plan with company

Generous paid time off

Professional development opportunities

Job summary

Placements24 seeks a Senior Bioprocess Engineer to optimize and scale biopharmaceutical production in Vereeniging. You will design and manage bioprocessing workflows, troubleshoot manufacturing challenges, and contribute to next-gen bioprocessing technologies.

The role requires 7+ years in biopharma process development, deep knowledge of upstream and downstream operations, and strong GMP/regulatory experience. Collaboration with manufacturing, QA, and regulatory teams is essential.

Qualifications

• MSc or PhD in Biochemical Engineering, Chemical Engineering, Biotechnology, or a related field.
• Minimum of 7 years of progressive experience in biopharmaceutical process development and manufacturing.
• In-depth knowledge of upstream (cell culture) and downstream (purification) bioprocessing operations.
• Experience with process modeling, statistical analysis, and Design of Experiments (DoE).
• Strong understanding of Good Manufacturing Practices (GMP) and regulatory requirements.

Responsibilities

• Design, develop, optimize, and scale up bioprocesses for the production of biologics.
• Manage and operate large-scale bioreactors, cell culture systems, and downstream purification equipment.
• Conduct process validation, troubleshoot deviations, and implement CAPAs.
• Analyze process data to identify opportunities for improvement in yield, efficiency, and product quality.
• Collaborate with cross-functional teams, including manufacturing, quality assurance, and regulatory affairs.

Skills

Biochemical engineering

Process modeling

DoE

Statistical analysis

Regulatory compliance

Education

MSc or PhD in Biochemical Engineering, Chemical Engineering, Biotechnology, or related field

Tools

Bioreactors

Downstream purification equipment

Process validation tools

Job description

About the Role

Our client is seeking a seasoned Senior Bioprocess Engineer to join their expanding operations in Vereeniging . This role is instrumental in optimizing and scaling up biopharmaceutical manufacturing processes, ensuring the efficient and robust production of therapeutic proteins and other biologics. You will design, implement, and manage bioprocessing workflows, troubleshoot complex manufacturing challenges, and contribute to the development of next-generation bioprocessing technologies. The ideal candidate will possess a strong foundation in biochemical engineering principles, extensive experience with large-scale bioreactors and downstream processing, and a commitment to driving operational excellence in a highly regulated industry, all within a collaborative and innovation-focused setting.

Key Responsibilities

• Design, develop, optimize, and scale up bioprocesses for the production of biologics.
• Manage and operate large-scale bioreactors, cell culture systems, and downstream purification equipment.
• Conduct process validation, troubleshoot deviations, and implement corrective and preventative actions (CAPAs).
• Analyze process data to identify opportunities for improvement in yield, efficiency, and product quality.
• Collaborate with cross-functional teams, including manufacturing, quality assurance, and regulatory affairs.

Requirements

• MSc or PhD in Biochemical Engineering, Chemical Engineering, Biotechnology, or a related field.
• Minimum of 7 years of progressive experience in biopharmaceutical process development and manufacturing.
• In-depth knowledge of upstream (cell culture) and downstream (purification) bioprocessing operations.
• Experience with process modeling, statistical analysis, and Design of Experiments (DoE).
• Strong understanding of Good Manufacturing Practices (GMP) and regulatory requirements.

Benefits

• Highly competitive salary and performance-based bonus structure.
• Comprehensive medical, dental, and vision insurance coverage.
• Retirement savings plan with company contributions.
• Generous paid time off and opportunities for professional development.

Key role in advancing biopharmaceutical production in Vereeniging .