Senior Biophysicist: Membrane & Protein Dynamics Lead (Soweto)

Placements24; Soweto; On-site; ZAR 900,000 - 1,400,000; Full time

Benefits offered by this job

Health insurance

Retirement plan

Professional development

Conference participation

State-of-the-art instrumentation

Job summary

Placements24 is seeking a Senior Biophysicist to lead experimental design and analysis of biomolecular systems in Soweto. The role focuses on protein structure-function, membrane biophysics, and molecular interactions, with access to state-of-the-art biophysical instrumentation.

The ideal candidate will have a PhD in a related field and 5+ years of biophysics experience, with proven publication records and strong computational skills to interpret experimental data.

Qualifications

• Ph.D. in Biophysics, Biochemistry, Physical Chemistry, or a related discipline.
• A minimum of 5 years of postdoctoral or industry experience in biophysics research.
• Demonstrated expertise in multiple biophysical techniques and instrumentation.
• Strong theoretical understanding of physical chemistry principles as applied to biological systems.

Responsibilities

• Design and conduct experiments to elucidate the physical properties of biomolecules and biological systems.
• Utilize and advance a variety of biophysical techniques including spectroscopy, calorimetry, SPR, ITC, and X-ray/cryo-EM.
• Develop and apply computational modeling to interpret data and predict molecular behavior.
• Characterize protein-ligand interactions, folding, aggregation, and membrane dynamics.
• Collaborate with biochemists, molecular biologists, and structural biologists on research questions.
• Analyze large datasets ensuring accuracy and rigor; publish findings.
• Mentor junior researchers and provide technical guidance to staff.
• Maintain and operate advanced biophysical instrumentation and troubleshoot issues.

Skills

Biophysics expertise

Protein structure-function

Data analysis

Computational modeling

Communication skills

Education

PhD in Biophysics/related

Tools

Spectroscopy (UV-Vis, Fluorescence, CD)

Calorimetry (ITC, DSC)

SPR

X-ray crystallography

Cryo-EM

Job description

Placements24 is seeking a Senior Biophysicist to lead experimental design and analysis of biomolecular systems in Soweto. The role focuses on protein structure-function, membrane biophysics, and molecular interactions, with access to state-of-the-art biophysical instrumentation.

The ideal candidate will have a PhD in a related field and 5+ years of biophysics experience, with proven publication records and strong computational skills to interpret experimental data.