Senior Biopharmaceutical Scientist

Placements24; Upington; On-site; ZAR 900,000 - 1,500,000; Full time

Benefits offered by this job

Competitive salary

Health, dental, and vision insurance

Generous retirement savings plan

Paid time off and holiday leave

Opportunities for professional growth

State-of-the-art laboratory facilities

Job summary

Placements24 invites applications for a Senior Biopharmaceutical Scientist to join a cutting-edge biopharma R&D team in Upington, Northern Cape. The role focuses on developing and characterizing biologics, including cell line development, protein expression, purification, and analytical assessment.

You will work hands-on with advanced techniques (HPLC, mass spectrometry, ELISA, SDS-PAGE) in a fast-paced, collaborative environment, contributing to regulatory-ready documentation and scientific

Qualifications

• PhD in Molecular Biology, Biochemistry, Biotechnology, or a closely related life science field.
• 5-7 years of post-doctoral or industry experience in biopharmaceutical R&D.
• Proven track record in development and characterization of biologics (e.g., monoclonal antibodies).
• Hands-on experience with mammalian cell culture, protein expression, and purification.
• Experience with analytical methods for biomolecule characterization and regulatory considerations.

Responsibilities

• Lead experiments for development and characterization of biopharmaceutical products.
• Develop and optimize cell culture processes for recombinant protein expression.
• Design and implement purification strategies for biologics using chromatography.
• Perform analytical characterization of biomolecules (structure, purity, activity).
• Utilize HPLC, mass spectrometry, ELISA, and SDS-PAGE in analyses.
• Collaborate with discovery, process development, and quality control teams.
• Prepare technical documentation for regulatory submissions and publications.

Skills

Molecular biology

Biochemistry

Biopharma development

Protein expression

HPLC

Mass spectrometry

DNA techniques

Education

PhD in Life Sciences

Tools

Chromatography

ELISA

SDS-PAGE

Job description

About the Role

Our client, a rapidly expanding biopharmaceutical company, is actively seeking a Senior Biopharmaceutical Scientist to join their advanced research and development team in Upington, Northern Cape . This role is at the forefront of developing and characterizing novel biologic therapeutics. You will play a key role in various stages of biopharmaceutical development, including cell line development, protein expression, purification, and analytical characterization. This is a hands-on, laboratory-based position requiring deep scientific expertise and a passion for innovation in the field of biologics. We are dedicated to pushing the boundaries of science to create life-changing treatments and are looking for a talented scientist to contribute to our mission. The ideal candidate will possess a strong background in molecular biology, biochemistry, or a related discipline, with proven experience in biopharmaceutical development. Excellent analytical skills, meticulous attention to detail, and the ability to work effectively in a collaborative, fast-paced environment are essential. This is a prime opportunity to contribute to groundbreaking research and advance your career in the biopharmaceutical industry.

Key Responsibilities

• Lead and execute experiments related to the development and characterization of biopharmaceutical products.
• Develop and optimize cell culture processes for the expression of recombinant proteins.
• Design and implement purification strategies for biologics using various chromatography techniques.
• Perform in-depth analytical characterization of biomolecules (e.g., protein structure, purity, activity).
• Utilise techniques such as HPLC, mass spectrometry, ELISA, and SDS-PAGE.
• Troubleshoot experimental challenges and develop innovative solutions.
• Analyze and interpret complex scientific data, generating comprehensive reports.
• Collaborate effectively with internal teams, including discovery research, process development, and quality control.
• Stay current with scientific literature and emerging technologies in biopharmaceutical development.
• Contribute to the preparation of technical documentation for regulatory submissions and publications.

Requirements

• PhD in Molecular Biology, Biochemistry, Biotechnology, or a closely related life science field.
• Minimum of 5-7 years of post-doctoral or industry experience in biopharmaceutical research and development.
• Proven track record in the development and characterization of biologics (e.g., monoclonal antibodies, recombinant proteins).
• Extensive hands-on experience with mammalian cell culture, protein expression, and purification techniques.
• Proficiency in various analytical methods for biomolecule characterization.
• Strong understanding of biopharmaceutical development processes and regulatory considerations.
• Excellent analytical, problem-solving, and critical thinking skills.
• Strong written and verbal communication skills, with the ability to present scientific findings clearly.
• Demonstrated ability to work independently and as part of a multidisciplinary team.
• Experience with quality control and assurance principles in biopharmaceutical manufacturing is an advantage.

Benefits

• Competitive salary and potential for performance-based bonuses.
• Comprehensive health, dental, and vision insurance coverage.
• Generous retirement savings plan.
• Paid time off and holiday leave.
• Opportunities for professional growth and skill development.
• Access to state-of-the-art laboratory facilities and equipment.
• A dynamic and innovative research environment.
• Relocation assistance may be available for qualified candidates.
• Contribution towards scientific conferences and publications.
• Involvement in the development of life-saving biologic therapies.