Senior Bioinformatician - Genomics Analysis

Placements24; Pietermaritzburg; Híbrido; ZAR 900.000 - 1.500.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Health insurance

Annual leave

Professional development

Hybrid work model

Career growth

Descripción de la vacante

Placements24 is seeking a Senior Bioinformatician to advance genomic data analysis in Pietermaritzburg, KwaZulu-Natal. The role focuses on designing and implementing analytical pipelines for NGS data and collaborating with biologists to interpret complex results.

The candidate should hold a PhD or MSc with 5+ years in bioinformatics, proficiency in Python/R/shell, and experience with BLAST, Ensembl, UCSC Genome Browser, and Galaxy. Cloud familiarity is a plus.

Formación

• Ph.D. or Master’s degree in Bioinformatics, Computational Biology, Computer Science, Statistics, or a related quantitative field.
• Minimum 5 years of post-degree experience in bioinformatics with a genomics focus.
• Proficiency in Python, R, and shell scripting.
• Hands-on experience with NGS data analysis workflows and related software.
• Strong statistical understanding and ability to apply methods to biological data.

Responsabilidades

• Develop, validate, and maintain robust bioinformatics pipelines for NGS data (WGS, RNA-Seq, ChIP-Seq).
• Analyze genomic and transcriptomic data, including variant calling and expression profiling.
• Collaborate with experimental biologists to define strategies and interpret results.
• Design statistical models to identify patterns or biomarkers.
• Contribute to new algorithms and computational tools for research questions.
• Manage and curate large genomic datasets, ensuring data integrity.
• Prepare reports, presentations, and manuscripts for publication.
• Stay updated on advancements in bioinformatics and genomics.

Conocimientos

Python

R

Shell scripting

Educación

PhD or Master’s degree in Bioinformatics, Computational Biology, Computer Science, Statistics, or related field

Herramientas

BLAST

Ensembl

UCSC Genome Browser

Galaxy

Descripción del empleo

About the Role

Our client, a pioneering force in **biotechnology research**, is seeking a highly skilled and motivated Senior Bioinformatician to join their dynamic team in Pietermaritzburg, KwaZulu-Natal. This role is crucial for advancing our understanding of complex biological systems through cutting-edge genomic data analysis. You will be instrumental in designing and implementing analytical pipelines, interpreting large-scale datasets, and contributing to groundbreaking scientific publications. The position offers a stimulating research environment, access to state-of-the-art computational resources, and the opportunity to work on projects with significant real-world impact in disease research and conservation genetics. This is a fantastic opportunity for a scientist passionate about leveraging computational methods to solve biological challenges.

Key Responsibilities

• Develop, validate, and maintain robust bioinformatics pipelines for next-generation sequencing (NGS) data analysis (e.g., WGS, RNA-Seq, ChIP-Seq).
• Perform comprehensive analysis of genomic and transcriptomic data, including variant calling, gene expression profiling, differential expression analysis, and pathway analysis.
• Collaborate closely with experimental biologists, geneticists, and other researchers to define analytical strategies and interpret results in a biological context.
• Design and implement statistical models to analyze complex biological data and identify significant patterns or biomarkers.
• Contribute to the development of new algorithms and computational tools to address specific research questions.
• Manage and curate large genomic datasets, ensuring data integrity and accessibility.
• Prepare high-quality reports, presentations, and scientific manuscripts for publication and dissemination of research findings.
• Stay abreast of the latest advancements in bioinformatics, genomics, and related computational biology fields.

Requirements

• A Ph.D. or Master’s degree in Bioinformatics, Computational Biology, Computer Science, Statistics, or a related quantitative field.
• Proven experience (minimum 5 years post-degree) in bioinformatics analysis, with a strong focus on genomics.
• Proficiency in programming languages such as Python, R, and shell scripting.
• Expertise in using standard bioinformatics tools and databases (e.g., BLAST, Ensembl, UCSC Genome Browser, Galaxy).
• Hands-on experience with NGS data analysis workflows and associated software.
• Strong understanding of statistical principles and their application in biological data analysis.
• Excellent problem-solving skills and the ability to work independently and as part of a collaborative team.
• Effective communication skills, both written and verbal, with the ability to explain complex technical concepts to a diverse audience.
• Experience with cloud computing platforms (AWS, GCP, Azure) is a plus.

Benefits

• Our client offers a competitive remuneration package, commensurate with experience and qualifications.
• Beyond a strong base salary, employees enjoy comprehensive health insurance coverage.
• A generous annual leave allowance.
• Opportunities for professional development, including conference attendance and further training.
• The company fosters a culture of innovation and collaboration, providing a supportive environment for career growth.
• We are committed to work-life balance, offering a hybrid work model that allows for flexibility while maintaining team synergy.
• Join a team that is making a real difference in scientific discovery in Pietermaritzburg.