Lead Bioinformatics Scientist

Placements24; Mossel Bay; Vor Ort; ZAR 1.200.000 - 1.800.000; Vollzeit

Benefits dieser Stelle

Bonuses

Medical insurance

Retirement plan

Professional development

Zusammenfassung

Placements24 in Mossel Bay is seeking a Lead Bioinformatics Scientist to guide computational biology efforts. You will develop pipelines for WGS/WES/RNA-Seq, mentor a team, and collaborate with biologists and clinicians to address research questions, applying ML and statistics to identify biomarkers.

The role emphasizes managing large datasets, advancing workflows (Snakemake/Nextflow), and communicating findings to diverse audiences while contributing to new study designs and software tools.

Qualifikationen

• PhD in Bioinformatics or related quantitative field.
• Minimum 6 years in bioinformatics or computational biology research.
• At least 2 years in leadership or supervisory roles.
• Strong experience with analysing NGS data.
• Proficiency in Python, R, and/or Perl.
• Experience with Snakemake and Nextflow workflows.
• Solid understanding of statistical genetics and ML.

Aufgaben

• Lead development, implementation, and maintenance of robust bioinformatics pipelines for high-throughput sequencing data (WGS, WES, RNA-Seq).
• Mentor and manage a team of bioinformatics scientists with technical direction.
• Collaborate with experimental biologists and clinicians to define research questions and strategies.
• Develop and apply statistical and ML methods for pattern discovery and biomarker identification.
• Ensure quality, integrity, and security of large genomic datasets.
• Contribute to study design and experimental protocols.
• Stay current with bioinformatics, genomics, and computational biology advancements.
• Communicate results to diverse audiences via reports and presentations.
• Contribute to internal software tools and databases.

Kenntnisse

NGS data analysis

Python

R

Perl

Machine Learning

Statistics

Leadership

Communication

High-performance computing

Ausbildung

PhD in Bioinformatics or related field

Tools

Snakemake

Nextflow

Jobbeschreibung

About the Role

Our client, a pioneering genomics research organization located in Mossel Bay, Western Cape, ZA , is seeking an accomplished Lead Bioinformatics Scientist to guide its computational biology efforts. This critical role involves developing and implementing advanced bioinformatics pipelines for the analysis of large-scale genomic and transcriptomic data. You will lead a team of bioinformaticians, collaborate with experimental biologists, and contribute to cutting-edge research in personalized medicine and disease diagnostics. The ideal candidate possesses deep expertise in sequence analysis, statistical genetics, and machine learning, with a proven ability to manage complex data projects. This is an exceptional opportunity to work at the forefront of bioinformatics in a growth-oriented organization based in the scenic region of Mossel Bay .

Key Responsibilities

• Lead the development, implementation, and maintenance of robust bioinformatics pipelines for high-throughput sequencing data analysis (e.g., WGS, WES, RNA-Seq).
• Manage and mentor a team of bioinformatics scientists, providing technical direction and project oversight.
• Collaborate closely with experimental biologists and clinicians to define research questions and analytical strategies.
• Develop and apply statistical and machine learning methods for pattern discovery and biomarker identification in complex biological datasets.
• Ensure the quality, integrity, and security of large genomic datasets.
• Contribute to the design of new research studies and experimental protocols.
• Stay current with the latest advancements in bioinformatics, genomics, and computational biology.
• Communicate complex analytical results effectively to diverse audiences through reports and presentations.
• Contribute to the development of internal software tools and databases.

Requirements

• Ph.D. in Bioinformatics, Computational Biology, Computer Science, Statistics, or a related quantitative field.
• Minimum of 6 years of experience in bioinformatics or computational biology research, with at least 2 years in a leadership or supervisory role.
• Strong expertise in analyzing next-generation sequencing (NGS) data.
• Proficiency in programming languages such as Python, R, and/or Perl.
• Experience with common bioinformatics tools, databases, and workflow management systems (e.g., Snakemake, Nextflow).
• Solid understanding of statistical genetics, machine learning, and data mining techniques.
• Experience in managing large datasets and high-performance computing environments.
• Excellent communication, collaboration, and problem-solving skills.
• Track record of publications in peer-reviewed journals.

Benefits

Our client offers a highly competitive salary, performance-based bonuses, and opportunities for career advancement.

The comprehensive benefits package includes excellent medical, dental, and vision coverage, as well as a retirement savings plan.

Generous paid time off and opportunities for professional development, including conference attendance and training, are provided.

Employees have access to state-of-the‑art computational resources and work in a dynamic, collaborative research environment in beautiful Mossel Bay .

The company is committed to fostering work-life balance and offers a supportive culture.